E Ben-Arye1, E Schiff2, E Hassan3, K Mutafoglu4, S Lev-Ari5, M Steiner6, O Lavie7, A Polliack8, M Silbermann9, E Lev10. 1. Integrative Oncology Program, The Oncology Service and Lin Medical Center, Clalit Health Services, Haifa, Israel; Complementary and Traditional Medicine Unit, Department of Family Medicine, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. Electronic address: eranben@netvision.net.il. 2. Department of Internal Medicine, Bnai-Zion Hospital, Haifa, Israel; Department for Complementary/Integrative Medicine, Law and Ethics,The International Center for Health, Law and Ethics, Haifa University, Haifa, Israel. 3. Department of Botany, National Research Centre, Dokki, Giza, Egypt. 4. Department of Pediatric Oncology, Institute of Oncology, Dokuz Eylul University, Inciralti Izmir, Turkey. 5. Complementary Medicine Unit, Tel-Aviv Medical Center, Tel-Aviv. 6. Department of Oncology, The Oncology Service and Lin Medical Center, Clalit Health Services, Haifa. 7. Department of Obstetrics and Gynecology, Carmel Medical Center, Haifa. 8. Department of Hematology, Hadassah University Hospital, Hebrew University Medical School, Jerusalem. 9. The Middle East Cancer Consortium, Haifa. 10. Department of Eretz Israel Studies, University of Haifa, Haifa, Israel.
Abstract
BACKGROUND: Based on traditional, historical, ethnobotanical, laboratory, and clinical findings, we present research framework aiming to identify Middle Eastern herbs that are worthy of further research for their anticancer potential. METHODS: A comprehensive research project was developed by a multinational team comprising family physicians, medicine specialists, oncologists, an Islamic medicine history specialist, a traditional medicine ethnobotanist, and a basic research scientist. The project followed two consecutive phases: (i) historical and ethnobotanical search for cancer-related keywords and (ii) Medline search for in vitro and in vivo studies. RESULTS: This search yielded 44 herbs associated with cancer care. The Medline search yielded 34 herbs of which 9 herbs were reported in various clinical studies. CONCLUSIONS: This multidisciplinary survey was found to be a valuable way to identify herbs with potential clinical significance in cancer care. Based on this pilot study, it is suggested that the Middle East can serve as a valuable region for future multicultural-oriented cancer research.
BACKGROUND: Based on traditional, historical, ethnobotanical, laboratory, and clinical findings, we present research framework aiming to identify Middle Eastern herbs that are worthy of further research for their anticancer potential. METHODS: A comprehensive research project was developed by a multinational team comprising family physicians, medicine specialists, oncologists, an Islamic medicine history specialist, a traditional medicine ethnobotanist, and a basic research scientist. The project followed two consecutive phases: (i) historical and ethnobotanical search for cancer-related keywords and (ii) Medline search for in vitro and in vivo studies. RESULTS: This search yielded 44 herbs associated with cancer care. The Medline search yielded 34 herbs of which 9 herbs were reported in various clinical studies. CONCLUSIONS: This multidisciplinary survey was found to be a valuable way to identify herbs with potential clinical significance in cancer care. Based on this pilot study, it is suggested that the Middle East can serve as a valuable region for future multicultural-oriented cancer research.
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