Literature DB >> 21446670

Direct displacement of alkoxy groups of vinylogous esters by Grignard reagents.

Anthony J Brockway1, Marcos González-López, James C Fettinger, Jared T Shaw.   

Abstract

The direct displacement of alkoxy groups from the β position of aromatic and unsaturated esters and ketones is described. The reaction is chemo- and regioselective, displaying wide substrate scope.
© 2011 American Chemical Society

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Year:  2011        PMID: 21446670      PMCID: PMC3180960          DOI: 10.1021/jo102537n

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

1.  Synthesis, resolution, and absolute stereochemistry of (-)-blestriarene C.

Authors:  Tetsutaro Hattori; Yuhi Shimazumi; Hitoshi Goto; Osamu Yamabe; Naoya Morohashi; Wataru Kawai; Sotaro Miyano
Journal:  J Org Chem       Date:  2003-03-21       Impact factor: 4.354

  1 in total
  2 in total

1.  Second-Generation Synthesis of (-)-Viriditoxin.

Authors:  Charles I Grove; Jared T Shaw
Journal:  Synthesis (Stuttg)       Date:  2012       Impact factor: 3.157

2.  Mechanism of alkoxy groups substitution by Grignard reagents on aromatic rings and experimental verification of theoretical predictions of anomalous reactions.

Authors:  Gonzalo Jiménez-Osés; Anthony J Brockway; Jared T Shaw; K N Houk
Journal:  J Am Chem Soc       Date:  2013-04-22       Impact factor: 15.419

  2 in total

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