Literature DB >> 2144391

Intradermal and intramuscular route for vaccination against hepatitis B.

M L González1, M Usandizaga, P Alomar, F Salvá, F Martín, M J Erroz, R Lardinois.   

Abstract

A recombinant hepatitis B vaccine was administered to high-risk hospital personnel by intramuscular (20 micrograms) or intradermal (2 micrograms) injections for the primary immunization (n = 69) with three doses and booster immunization (n = 51) with one dose. Basic vaccination performed intramuscularly gave rise to significantly higher seroconversion levels (97.2% versus 78.1%) and geometric mean titres of antibody (1649 versus 126 IUl-1) as compared with the intradermal route. Intradermal administration did not boost antibody titres in patients previously vaccinated intradermally. Adverse reactions were not serious or severe. The intramuscular route is recommended as the procedure of choice when vaccinating against hepatitis B.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2144391     DOI： 10.1016/0264-410x(90)90102-r

Source DB:  PubMed          Journal:  Vaccine        ISSN： 0264-410X            Impact factor:   3.641


  5 in total

1.  Vaccination against hepatitis B: comparison of intradermal and intramuscular administration of plasma derived and recombinant vaccines.

Authors:  C D Payton; D A Scarisbrick; S Sikotra; A J Flower
Journal:  Epidemiol Infect       Date:  1993-02       Impact factor: 2.451

2.  Response to a booster dose 18 months after a low anti-HBs response (10-99 IU/l) to three doses of intradermally or intramuscularly administered recombinant hepatitis B vaccine.

Authors:  J Struve; B Aronsson; B Frenning; M Forsgren; O Weiland
Journal:  Infection       Date:  1995 Jan-Feb       Impact factor: 3.553

3.  Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery.

Authors:  Joel Meyer; Stephanie A Harris; Iman Satti; Ian D Poulton; Hazel C Poyntz; Rachel Tanner; Rosalind Rowland; Kristin L Griffiths; Helen A Fletcher; Helen McShane
Journal:  Vaccine       Date:  2012-12-21       Impact factor: 3.641

Review 4.  Fractional dose of intradermal compared to intramuscular and subcutaneous vaccination - A systematic review and meta-analysis.

Authors:  Jenny L Schnyder; Cornelis A De Pijper; Hannah M Garcia Garrido; Joost G Daams; Abraham Goorhuis; Cornelis Stijnis; Frieder Schaumburg; Martin P Grobusch
Journal:  Travel Med Infect Dis       Date:  2020-09-06       Impact factor: 6.211

5.  Successful response of intradermal hepatitis B vaccine in nonresponders of intramuscular hepatitis B vaccine in general and hemodialysis population.

Authors:  Farina M Hanif; Nasir Mehmood; Zain Majid; Nasir H Luck; S Mudassir Laeeq; Abbas A Tasneem; Muhammad Manzoor Ul Haque
Journal:  Saudi J Gastroenterol       Date:  2020-10-28       Impact factor: 2.485
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.