Literature DB >> 21443448

Treatment of obsessive compulsive disorder.

Martin E Franklin1, Edna B Foa.   

Abstract

Obsessive compulsive disorder (OCD) is characterized by the presence of intrusive, anxiety-provoking thoughts, images, or impulses along with repetitive behaviors or mental acts designed to reduce obsessional distress. OCD is associated with significant functional impairment, psychiatric comorbidity, and compromised quality of life. Fortunately, substantive progress has been made in the past several decades in the development and empirical evaluation of treatments for OCD across the developmental spectrum. The current review begins with a discussion of the clinical presentation of OCD and psychological theories regarding its etiology and maintenance. A detailed discussion follows of exposure plus response prevention, the psychosocial treatment that has garnered the most evidence for its efficacy. A summary of the extant treatment outcome literature related to exposure plus response prevention as well as cognitive therapies, pharmacotherapies, and combined approaches is then presented. Recommendations for future clinical and research directions are then provided.
© 2011 by Annual Reviews. All rights reserved

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Year:  2011        PMID: 21443448     DOI: 10.1146/annurev-clinpsy-032210-104533

Source DB:  PubMed          Journal:  Annu Rev Clin Psychol        ISSN: 1548-5943            Impact factor:   18.561


  36 in total

1.  A Cross Species Approach to Understanding DBS Modulation of Fear.

Authors:  Jose Rodriguez-Romaguera; Benjamin D Greenberg; Suzanne N Haber; Gregory J Quirk
Journal:  Brain Stimul       Date:  2015-07-28       Impact factor: 8.955

2.  Basolateral amygdala input to the medial prefrontal cortex controls obsessive-compulsive disorder-like checking behavior.

Authors:  Tingting Sun; Zihua Song; Yanghua Tian; Wenbo Tian; Chunyan Zhu; Gongjun Ji; Yudan Luo; Shi Chen; Likui Wang; Yu Mao; Wen Xie; Hui Zhong; Fei Zhao; Min-Hua Luo; Wenjuan Tao; Haitao Wang; Jie Li; Juan Li; Jiangning Zhou; Kai Wang; Zhi Zhang
Journal:  Proc Natl Acad Sci U S A       Date:  2019-02-11       Impact factor: 11.205

3.  Family-based treatment of early childhood obsessive-compulsive disorder: the Pediatric Obsessive-Compulsive Disorder Treatment Study for Young Children (POTS Jr)--a randomized clinical trial.

Authors:  Jennifer Freeman; Jeffrey Sapyta; Abbe Garcia; Scott Compton; Muniya Khanna; Chris Flessner; David FitzGerald; Christian Mauro; Rebecca Dingfelder; Kristen Benito; Julie Harrison; John Curry; Edna Foa; John March; Phoebe Moore; Martin Franklin
Journal:  JAMA Psychiatry       Date:  2014-06       Impact factor: 21.596

Review 4.  Pediatric indications for deep brain stimulation.

Authors:  Matthew F DiFrancesco; Casey H Halpern; Howard H Hurtig; Gordon H Baltuch; Gregory G Heuer
Journal:  Childs Nerv Syst       Date:  2012-07-25       Impact factor: 1.475

Review 5.  Obsessive-compulsive and tic-related disorders.

Authors:  Martin E Franklin; Julie P Harrison; Kristin L Benavides
Journal:  Child Adolesc Psychiatr Clin N Am       Date:  2012-06-16

6.  Treating a 16 Year Old with a History of Severe Bullying: Supplementing Cognitive Behavioural Therapy with EMDR within the Context of a Case Formulation Approach.

Authors:  Alice Taylor; Niel H McLachlan
Journal:  J Child Adolesc Trauma       Date:  2019-05-06

7.  Optogenetic stimulation of lateral orbitofronto-striatal pathway suppresses compulsive behaviors.

Authors:  Eric Burguière; Patrícia Monteiro; Guoping Feng; Ann M Graybiel
Journal:  Science       Date:  2013-06-07       Impact factor: 47.728

8.  Sudden gains in internet-based cognitive behaviour therapy for severe health anxiety.

Authors:  Erik Hedman; Mats Lekander; Brjánn Ljótsson; Nils Lindefors; Christian Rück; Stefan G Hofmann; Erik Andersson; Gerhard Andersson; Stefan M Schulz
Journal:  Behav Res Ther       Date:  2014-01-11

9.  Exposure and response prevention helps adults with obsessive-compulsive disorder who do not respond to pharmacological augmentation strategies.

Authors:  Carmen P McLean; Laurie J Zandberg; Page E Van Meter; Joseph K Carpenter; Helen Blair Simpson; Edna B Foa
Journal:  J Clin Psychiatry       Date:  2015-12       Impact factor: 4.384

10.  In a double-blind, randomized and placebo-controlled trial, adjuvant memantine improved symptoms in inpatients suffering from refractory obsessive-compulsive disorders (OCD).

Authors:  Mohammad Haghighi; Leila Jahangard; Hamid Mohammad-Beigi; Hafez Bajoghli; Hassan Hafezian; Alireza Rahimi; Hamid Afshar; Edith Holsboer-Trachsler; Serge Brand
Journal:  Psychopharmacology (Berl)       Date:  2013-03-23       Impact factor: 4.530

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