Literature DB >> 21443321

A randomized controlled trial of cognitive-behavioral therapy for generalized anxiety disorder with integrated techniques from emotion-focused and interpersonal therapies.

Michelle G Newman1, Louis G Castonguay, Thomas D Borkovec, Aaron J Fisher, James F Boswell, Lauren E Szkodny, Samuel S Nordberg.   

Abstract

OBJECTIVE: Recent models suggest that generalized anxiety disorder (GAD) symptoms may be maintained by emotional processing avoidance and interpersonal problems.
METHOD: This is the first randomized controlled trial to test directly whether cognitive-behavioral therapy (CBT) could be augmented with the addition of a module targeting interpersonal problems and emotional processing. Eighty-three primarily White participants (mean age = 37) with a principle diagnosis of GAD were recruited from the community. Participants were assigned randomly to CBT plus supportive listening (n = 40) or to CBT plus interpersonal and emotional processing therapy (n = 43) within a study using an additive design. Doctoral-level psychologists with full-time private practices treated participants in an outpatient clinic. Using blind assessors, participants were assessed at pretreatment, posttreatment, 6-month, 1-year, and 2-year follow-up with a composite of self-report and assessor-rated GAD symptom measures (the Penn State Worry Questionnaire; T. J. Meyer, M. L. Miller, R. L. Metzger, & T. D. Borkovec, 1990; Hamilton Anxiety Rating Scale; M. Hamilton, 1959; assessor severity rating; State-Trait Anxiety Inventory-Trait Version; C. D. Spielberger, R. L. Gorsuch, R. Lushene, P. R. Vagg, & G. A. Jacobs, 1983) as well as with indices of clinically significant change.
RESULTS: Mixed models analysis of all randomized participants showed very large within-treatment effect sizes for both treatments (CI = [-.40, -.28], d = 1.86) with no significant differences at post (CI = [-.09, .07], d = .07) or 2-year follow-up (CI = [-.01, .01]), d = .12). There was also no statistical difference between compared treatments on clinically significant change based on chi-square analysis.
CONCLUSIONS: Interpersonal and emotional processing techniques may not augment CBT for all GAD participants. Trial Registry name: Clinical Trials.gov, Identifier: NCT00951652. (c) 2011 APA, all rights reserved.

Entities:  

Mesh:

Year:  2011        PMID: 21443321      PMCID: PMC3078794          DOI: 10.1037/a0022489

Source DB:  PubMed          Journal:  J Consult Clin Psychol        ISSN: 0022-006X


  33 in total

1.  Effects of worry on physiological and subjective reactivity to emotional stimuli in generalized anxiety disorder and nonanxious control participants.

Authors:  Sandra J Llera; Michelle G Newman
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2.  Development and validation of the Penn State Worry Questionnaire.

Authors:  T J Meyer; M L Miller; R L Metzger; T D Borkovec
Journal:  Behav Res Ther       Date:  1990

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Authors:  Robert Gallop; Giorgio A Tasca
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4.  Preliminary evidence for an emotion dysregulation model of generalized anxiety disorder.

Authors:  Douglas S Mennin; Richard G Heimberg; Cynthia L Turk; David M Fresco
Journal:  Behav Res Ther       Date:  2004-12-10

Review 5.  Psychotherapy for generalized anxiety disorder.

Authors:  T D Borkovec; A M Ruscio
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6.  Current and lifetime comorbidity of the DSM-IV anxiety and mood disorders in a large clinical sample.

Authors:  T A Brown; L A Campbell; C L Lehman; J R Grisham; R B Mancill
Journal:  J Abnorm Psychol       Date:  2001-11

7.  Efficacy of applied relaxation and cognitive-behavioral therapy in the treatment of generalized anxiety disorder.

Authors:  T D Borkovec; E Costello
Journal:  J Consult Clin Psychol       Date:  1993-08

8.  Expectancy/Credibility Change as a Mediator of Cognitive Behavioral Therapy for Generalized Anxiety Disorder: Mechanism of Action or Proxy for Symptom Change?

Authors:  Michelle G Newman; Aaron J Fisher
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9.  A component analysis of cognitive-behavioral therapy for generalized anxiety disorder and the role of interpersonal problems.

Authors:  T D Borkovec; Michelle G Newman; Aaron L Pincus; Richard Lytle
Journal:  J Consult Clin Psychol       Date:  2002-04

10.  Efficacy of an acceptance-based behavior therapy for generalized anxiety disorder: evaluation in a randomized controlled trial.

Authors:  Lizabeth Roemer; Susan M Orsillo; Kristalyn Salters-Pedneault
Journal:  J Consult Clin Psychol       Date:  2008-12
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  37 in total

Review 1.  Advances in psychotherapy for generalized anxiety disorder.

Authors:  Eric J Garfinkle; Evelyn Behar
Journal:  Curr Psychiatry Rep       Date:  2012-06       Impact factor: 5.285

2.  How many treatment sessions and patients are needed to create a stable score of adherence and competence in the treatment of cocaine dependence?

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Journal:  Psychother Res       Date:  2012-03-26

3.  A Case of Premature Termination in a Treatment for Generalized Anxiety Disorder.

Authors:  James F Boswell; Sandra Llera; Michelle G Newman; Louis G Castonguay
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4.  Interpersonal Problems Predict Differential Response to Cognitive Versus Behavioral Treatment in a Randomized Controlled Trial.

Authors:  Michelle G Newman; Nicholas C Jacobson; Thane M Erickson; Aaron J Fisher
Journal:  Behav Ther       Date:  2016-06-06

Review 5.  Critical review of outcome research on interpersonal psychotherapy for anxiety disorders.

Authors:  John C Markowitz; Joshua Lipsitz; Barbara L Milrod
Journal:  Depress Anxiety       Date:  2014-02-03       Impact factor: 6.505

6.  Expectancies, working alliance, and outcome in transdiagnostic and single diagnosis treatment for anxiety disorders: An investigation of mediation.

Authors:  Shannon Sauer-Zavala; James F Boswell; Kate H Bentley; Johanna Thompson-Hollands; Todd J Farchione; David H Barlow
Journal:  Cognit Ther Res       Date:  2017-04-25

7.  Social criticism moderates the relationship between anxiety and depression 10 years later.

Authors:  Kayla A Lord; Nicholas C Jacobson; Michael K Suvak; Michelle G Newman
Journal:  J Affect Disord       Date:  2020-05-21       Impact factor: 4.839

8.  Self- and other-perceptions of interpersonal problems: Effects of generalized anxiety, social anxiety, and depression.

Authors:  Ki Eun Shin; Michelle G Newman
Journal:  J Anxiety Disord       Date:  2019-04-22

Review 9.  Worry and generalized anxiety disorder: a review and theoretical synthesis of evidence on nature, etiology, mechanisms, and treatment.

Authors:  Michelle G Newman; Sandra J Llera; Thane M Erickson; Amy Przeworski; Louis G Castonguay
Journal:  Annu Rev Clin Psychol       Date:  2013       Impact factor: 18.561

10.  United we stand: emphasizing commonalities across cognitive-behavioral therapies.

Authors:  Douglas S Mennin; Kristen K Ellard; David M Fresco; James J Gross
Journal:  Behav Ther       Date:  2013-03-04
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