Literature DB >> 21442561

[Standardized x-ray reports of the spine in osteogenesis imperfecta].

F Koerber1, O Semler, A W Demant, S Koerber, E Schönau, K-J Lackner.   

Abstract

PURPOSE: In this study we present a standard for radiological reports in patients with osteogenesis imperfecta (OI). The parameters can be used to describe X-rays of the lateral spine and give an impartial description of anatomical structures during a treatment with bisphosphonates.
MATERIAL AND METHODS: In this retrospective analysis we included 48 patients with OI (31 female, 17 male [1.5 months - 19 years, mean age 9.0 years]). Lateral spine X-rays were analyzed by 2 radiologists before and during treatment. The parameters of the standardized report are degree of kyphoscoliosis, compression of single vertebrae, predominant type of vertebral deformities and extent of vertebral compression (score 1 - 5).
RESULTS: There was no clear trend in the change of compression of single vertebrae. Some vertebrae with ventral compression showed an upgrowth to vertebrae with harmonic compression. Other deformities showed only marginal changes. In 26 patients the kyphoscoliosis improved (mean 10 degrees), in 36 patients the thoracic vertebrae compression increased and in 30 patients the vertebral height in the lumbar spine increased. The improvement of vertebral height was 1 point in the thoracic and lumbar spine.
CONCLUSION: We propose a standardized report of X-rays of the lateral spine in patients with OI with quantitative and semiquantitative parameters using morphological criteria. These include compression of single vertebrae, degree of kyphoscoliosis, vertebral deformities and the severity of vertebral compression in the thoracic and lumbar spine. © Georg Thieme Verlag KG Stuttgart · New York.

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Year:  2011        PMID: 21442561     DOI: 10.1055/s-0029-1246073

Source DB:  PubMed          Journal:  Rofo        ISSN: 1438-9010


  3 in total

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Journal:  BMC Musculoskelet Disord       Date:  2014-12-13       Impact factor: 2.362

2.  Safety and efficacy of denosumab in children with osteogenesis imperfect--a first prospective trial.

Authors:  H Hoyer-Kuhn; J Franklin; G Allo; M Kron; C Netzer; P Eysel; B Hero; E Schoenau; O Semler
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3.  Roentgenographic Evaluation of the Spine in Patients With Osteogenesis Imperfecta.

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Journal:  Medicine (Baltimore)       Date:  2015-11       Impact factor: 1.817

  3 in total

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