Literature DB >> 21438106

Differentiating serine and cysteine protease mechanisms by new covalent QSAR descriptors.

Michael Shokhen1, Tamar Traube, Subramaniam Vijayakumar, Michal Hirsch, Neta Uritsky, Amnon Albeck.   

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Year:  2011        PMID： 21438106      PMCID： PMC3088911          DOI： 10.1002/cbic.201000459

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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  12 in total

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2.  The mechanism of papain inhibition by peptidyl aldehydes.

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3.  Enzyme isoselective inhibitors: a tool for binding-trend analysis.

Authors:  Rachel Ozeri; Netaly Khazanov; Nurit Perlman; Michael Shokhen; Amnon Albeck
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4.  Enzyme isoselective inhibitors: application to drug design.

Authors:  Michael Shokhen; Netaly Khazanov; Amnon Albeck
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5.  In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug design.

Authors:  Michael J Costanzo; Harold R Almond; Leonard R Hecker; Mary R Schott; Stephen C Yabut; Han-Cheng Zhang; Patricia Andrade-Gordon; Thomas W Corcoran; Edward C Giardino; Jack A Kauffman; Joan M Lewis; Lawrence de Garavilla; Barbara J Haertlein; Bruce E Maryanoff
Journal:  J Med Chem       Date:  2005-03-24       Impact factor: 7.446

6.  Mechanism of association of N-acetyl-L-phenylalanylglycinal to papain.

Authors:  A Frankfater; T Kuppy
Journal:  Biochemistry       Date:  1981-09-15       Impact factor: 3.162

7.  Factors determining the relative stability of anionic tetrahedral complexes in serine protease catalysis and inhibition.

Authors:  M Shokhen; A Albeck
Journal:  Proteins       Date:  2000-07-01

8.  Design of potent, selective, and orally bioavailable inhibitors of cysteine protease cathepsin k.

Authors:  Francis X Tavares; Virginia Boncek; David N Deaton; Anne M Hassell; Stacey T Long; Aaron B Miller; Alan A Payne; Larry R Miller; Lisa M Shewchuk; Kevin Wells-Knecht; Derril H Willard; Lois L Wright; Hui-Qiang Zhou
Journal:  J Med Chem       Date:  2004-01-29       Impact factor: 7.446

9.  Challenging a paradigm: theoretical calculations of the protonation state of the Cys25-His159 catalytic diad in free papain.

Authors:  Michael Shokhen; Netaly Khazanov; Amnon Albeck
Journal:  Proteins       Date:  2009-12

Review 10.  Inhibitors of proteases and amide hydrolases that employ an alpha-ketoheterocycle as a key enabling functionality.

Authors:  Bruce E Maryanoff; Michael J Costanzo
Journal:  Bioorg Med Chem       Date:  2007-11-06       Impact factor: 3.641
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1.  EMBM - a new enzyme mechanism-based method for rational design of chemical sites of covalent inhibitors.

Authors:  Tamar Traube; Subramaniam Vijayakumar; Michal Hirsch; Neta Uritsky; Michael Shokhen; Amnon Albeck
Journal:  J Chem Inf Model       Date:  2010-11-19       Impact factor: 4.956

2.  Insight into substituent effects in Cal-B catalyzed transesterification by combining experimental and theoretical approaches.

Authors:  Zhong Ni; Xianfu Lin
Journal:  J Mol Model       Date:  2012-08-25       Impact factor: 1.810

3.  Characterization and functional assay of apsup (Lyxy105) from Lymantria xylina multiple nucleopolyhedrovirus (LyxyMNPV).

Authors:  Ju-Chun Chang; Zih-Ting Chang; Yu-Feng Huang; Se Jin Lee; Jae Su Kim; Yu-Shin Nai
Journal:  Virus Genes       Date:  2018-06-06       Impact factor: 2.332

4.  Peptidyl cyclopropenones: reversible inhibitors, irreversible inhibitors, or substrates of cysteine proteases?

Authors:  Meital Cohen; Uriel Bretler; Amnon Albeck
Journal:  Protein Sci       Date:  2013-04-29       Impact factor: 6.725

5.  Cysteine protease inhibition by nitrile-based inhibitors: a computational study.

Authors:  Matthew G Quesne; Richard A Ward; Sam P de Visser
Journal:  Front Chem       Date:  2013-12-27       Impact factor: 5.221
  5 in total

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