Literature DB >> 21437170

Complete atrioventricular block-induced Torsade de pointes, manifested by epilepsy.

Jun Han Jeon1, Sung Ho Her, Jung Yeon Chin, Ki Hoon Park, Hee Jeong Yoon, Jong Min Lee, Seung Won Jin.   

Abstract

Complete atrioventricular (AV) block is frequently regarded as a cause of informed syncopal attacks, even though the escape rhythm is maintained. Torsade de pointes (TdP) may be a significant complication of AV block associated with QT prolongation. Here, we report the case of a 42-year-old female who was referred to our hospital due to recurrent seizure-like attacks while taking anti-convulsant drugs at a psychiatric hospital. TdP with a long QT interval (corrected QT = 0.591 seconds) was observed on an electrocardiogram (ECG) taken in the emergency department. The patient's drug history revealed olanzapine as the suspicious agent. Even after the medication was stopped, however, the QT interval remained within an abnormal range and multiple episodes of TdP and related seizure-like symptoms were found via ECG monitoring. A permanent pacemaker was thus implanted, and the ventricular rate was set at over 80 beats/min. There was no recurrence of tachyarrhythmia or other symptoms.

Entities:  

Keywords:  Complete atrioventricular block; Pacemaker; Torsade de pointes

Mesh:

Substances:

Year:  2011        PMID: 21437170      PMCID: PMC3056264          DOI: 10.3904/kjim.2011.26.1.99

Source DB:  PubMed          Journal:  Korean J Intern Med        ISSN: 1226-3303            Impact factor:   2.884


  8 in total

1.  QTc prolongation and high-dose olanzapine.

Authors:  Sean Dineen; Kirk Withrow; Liouda Voronovitch; Firoz Munshi; Mohammad Wally Nawbary; Steven Lippmann
Journal:  Psychosomatics       Date:  2003 Mar-Apr       Impact factor: 2.386

2.  A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs.

Authors:  Sathapana Kongsamut; Jiesheng Kang; Xiao-Liang Chen; Joachim Roehr; David Rampe
Journal:  Eur J Pharmacol       Date:  2002-08-16       Impact factor: 4.432

3.  Torsade De Pointes, an atypical ventricular tachycardia.

Authors:  D M Krikler; P V Curry
Journal:  Br Heart J       Date:  1976-02

4.  ACC/AHA guidelines for implantation of cardiac pacemakers and antiarrhythmia devices: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Pacemaker Implantation).

Authors:  G Gregoratos; M D Cheitlin; A Conill; A E Epstein; C Fellows; T B Ferguson; R A Freedman; M A Hlatky; G V Naccarelli; S Saksena; R C Schlant; M J Silka; J L Ritchie; R J Gibbons; M D Cheitlin; K A Eagle; T J Gardner; R P Lewis; R A O'Rourke; T J Ryan; A Garson
Journal:  J Am Coll Cardiol       Date:  1998-04       Impact factor: 24.094

5.  Polymorphous ventricular tachycardia and atrioventricular block.

Authors:  B Strasberg; J Kusniec; S Erdman; R F Lewin; A Arditti; S Sclarovsky; J Agmon
Journal:  Pacing Clin Electrophysiol       Date:  1986-07       Impact factor: 1.976

Review 6.  Long QT syndromes and torsade de pointes.

Authors:  S Viskin
Journal:  Lancet       Date:  1999-11-06       Impact factor: 79.321

7.  Bradycardia-induced abnormal QT prolongation in patients with complete atrioventricular block with torsades de pointes.

Authors:  T Kurita; T Ohe; N Marui; N Aihara; H Takaki; S Kamakura; M Matsuhisa; K Shimomura
Journal:  Am J Cardiol       Date:  1992-03-01       Impact factor: 2.778

Review 8.  Torsade de pointes.

Authors:  Nabil El-Sherif; Gioia Turitto
Journal:  Curr Opin Cardiol       Date:  2003-01       Impact factor: 2.161

  8 in total
  1 in total

Review 1.  QTc Interval Prolongation with Therapies Used to Treat Patients with Parkinson's Disease Psychosis: A Narrative Review.

Authors:  Yasar Torres-Yaghi; Amelia Carwin; Jacob Carolan; Steven Nakano; Fahd Amjad; Fernando Pagan
Journal:  Neuropsychiatr Dis Treat       Date:  2021-12-24       Impact factor: 2.570

  1 in total

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