Literature DB >> 2143649

Effect of methyl isocyanate (MIC) on rat erythrocytes.

D Agrawal1, G S Gupta, J S Shukla, K K Dutta, P K Ray.   

Abstract

Changes in surface morphology of rat erythrocytes were studied by scanning electron microscopy after a single and repeated exposure of methyl isocyanate under static conditions. Marked morphological changes (echinocytes and spherocytes) were observed, followed by an increase in osmotic fragility of the erythrocyte membrane. The activity of the membrane bound enzyme adenosine triphosphatase (Na+, K+, Mg++) was inhibited.

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Year:  1990        PMID： 2143649     DOI： 10.1007/bf01972995

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


  10 in total

1.  The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes.

Authors:  J T DODGE; C MITCHELL; D J HANAHAN
Journal:  Arch Biochem Biophys       Date:  1963-01       Impact factor: 4.013

2.  THE OSMOTIC RESISTANCE (FRAGILITY) OF HUMAN RED CELLS.

Authors:  A K Parpart; P B Lorenz; E R Parpart; J R Gregg; A M Chase
Journal:  J Clin Invest       Date:  1947-07       Impact factor: 14.808

3.  Effect of exposure to toxic gas on the population of Bhopal: Part III--Assessment of toxic manifestations in humans--haematological and biochemical studies.

Authors:  R C Srivastava; B N Gupta; M Athar; J R Behari; R S Dwivedi; S K Hasan; R S Bharti; A Singh; M Misra; P K Ray
Journal:  Indian J Exp Biol       Date:  1988-03       Impact factor: 0.818

Review 4.  Methyl isocyanate: a review of health effects research since Bhopal.

Authors:  J R Bucher
Journal:  Fundam Appl Toxicol       Date:  1987-10

5.  The effects of sickling on ion transport. I. Effect of sickling on potassium transport.

Authors:  D C TOSTESON; E CARLSEN; E T DUNHAM
Journal:  J Gen Physiol       Date:  1955-09-20       Impact factor: 4.086

6.  Inhalation toxicity studies of methyl isocyanate (MIC) in rats: Part I--Pulmonary pathology and genotoxicity evaluation.

Authors:  K K Dutta; G S Gupta; A Mishra; A Joshi; G S Tandon; P K Ray
Journal:  Indian J Exp Biol       Date:  1988-03       Impact factor: 0.818

7.  Inhalation toxicity studies on methyl isocyanate (MIC) in rats: Part II--Biochemical studies on hemolysates, lactate dehydrogenase, isoenzymes and lipid peroxidation.

Authors:  G S Gupta; F N Jaffery; K K Dutta; P N Viswanathan; A Mishra; P K Ray
Journal:  Indian J Exp Biol       Date:  1988-03       Impact factor: 0.818

8.  Adhesion of cells to surfaces coated with polylysine. Applications to electron microscopy.

Authors:  D Mazia; G Schatten; W Sale
Journal:  J Cell Biol       Date:  1975-07       Impact factor: 10.539

9.  Biological effects of short-term, high-concentration exposure to methyl isocyanate. IV. Influence on the oxygen-binding properties of guinea pig blood.

Authors:  L A Maginniss; J M Szewczak; C M Troup
Journal:  Environ Health Perspect       Date:  1987-06       Impact factor: 9.031

10.  Biological effects of short-term, high-concentration exposure to methyl isocyanate. II. Blood chemistry and hematologic evaluations.

Authors:  C M Troup; D E Dodd; E H Fowler; F R Frank
Journal:  Environ Health Perspect       Date:  1987-06       Impact factor: 9.031
  10 in total
  6 in total

1.  Modulation of microsomal membrane associated detoxication enzymes activity by methyl isocyanate (MIC) exposure.

Authors:  A Mishra; P D Dwivedi; A S Verma; J Mishra; M Sinha; K K Dutta; P K Ray
Journal:  Bull Environ Contam Toxicol       Date:  1991-11       Impact factor: 2.151

2.  Effect of methyl isocyanate on rabbit cardiac Na+, K(+)-ATPase.

Authors:  K Jeevaratnam
Journal:  Arch Toxicol       Date:  1995       Impact factor: 5.153

3.  Proceedings of the 2011 National Toxicology Program Satellite Symposium.

Authors:  Gary Boorman; Torrie A Crabbs; Holly Kolenda-Roberts; Ken Latimer; Andrew D Miller; Kathleen B Muravnick; Abraham Nyska; Ricardo Ochoa; Ingrid D Pardo; Yuval Ramot; Deepa B Rao; JoAnn Schuh; Andrew Suttie; Greg S Travlos; Jerrold M Ward; Jeffrey C Wolf; Susan A Elmore
Journal:  Toxicol Pathol       Date:  2011-11-16       Impact factor: 1.902

4.  Influence of nitrovasodilators and endothelin-1 on rheology of human blood in vitro.

Authors:  R Walter; M Mark; R Gaudenz; L G Harris; W H Reinhart
Journal:  Br J Pharmacol       Date:  1999-10       Impact factor: 8.739

5.  Evaluating the effects of anticoagulant rodenticide bromadiolone in Wistar rats co-exposed to vitamin K: impact on blood-liver axis and brain oxidative status.

Authors:  Damir Suljević; Saida Ibragić; Maja Mitrašinović-Brulić; Muhamed Fočak
Journal:  Mol Cell Biochem       Date:  2021-11-23       Impact factor: 3.396

6.  Acute toxicity of methyl isocyanate in rabbit: in vitro and in vivo effects on rabbit erythrocyte membrane.

Authors:  K Jeevaratnam; C S Vaidyanathan
Journal:  Arch Environ Contam Toxicol       Date:  1992-04       Impact factor: 2.804
  6 in total

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