Literature DB >> 21433240

Ruthenium(II) metallo-intercalators: DNA imaging and cytotoxicity.

Martin R Gill1, Hanan Derrat, Carl G W Smythe, Giuseppe Battaglia, Jim A Thomas.   

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Year:  2011        PMID： 21433240     DOI： 10.1002/cbic.201000782

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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  16 in total

1.  Effects of chirality on the intracellular localization of binuclear ruthenium(II) polypyridyl complexes.

Authors:  Frida R Svensson; Johanna Andersson; Helene L Åmand; Per Lincoln
Journal:  J Biol Inorg Chem       Date:  2012-02-05       Impact factor: 3.358

2.  Mitochondria are the primary target in the induction of apoptosis by chiral ruthenium(II) polypyridyl complexes in cancer cells.

Authors:  Jin-Quan Wang; Ping-Yu Zhang; Chen Qian; Xiao-Juan Hou; Liang-Nian Ji; Hui Chao
Journal:  J Biol Inorg Chem       Date:  2013-11-28       Impact factor: 3.358

3.  Multifaceted interplay between lipophilicity, protein interaction and luminescence parameters of non-intercalative ruthenium(II) polypyridyl complexes controlling cellular imaging and cytotoxic properties.

Authors:  Olga Mazuryk; Katarzyna Magiera; Barbara Rys; Franck Suzenet; Claudine Kieda; Małgorzata Brindell
Journal:  J Biol Inorg Chem       Date:  2014-08-26       Impact factor: 3.358

4.  Targeting the endoplasmic reticulum with a membrane-interactive luminescent ruthenium(ii) polypyridyl complex†Electronic supplementary information (ESI) available: Experimental details, characterization of 2 and Fig. S1-S6. See DOI: 10.1039/c3sc51725jClick here for additional data file.

Authors:  Martin R Gill; Denis Cecchin; Michael G Walker; Raminder S Mulla; Giuseppe Battaglia; Carl Smythe; Jim A Thomas
Journal:  Chem Sci       Date:  2013-10-16       Impact factor: 9.825

5.  A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition.

Authors:  Martin R Gill; Siti Norain Harun; Swagata Halder; Ramon A Boghozian; Kristijan Ramadan; Haslina Ahmad; Katherine A Vallis
Journal:  Sci Rep       Date:  2016-08-25       Impact factor: 4.379

6.  Photochemically active DNA-intercalating ruthenium and related complexes - insights by combining crystallography and transient spectroscopy.

Authors:  Christine J Cardin; John M Kelly; Susan J Quinn
Journal:  Chem Sci       Date:  2017-04-12       Impact factor: 9.825

7.  A three-in-one-bullet for oesophageal cancer: replication fork collapse, spindle attachment failure and enhanced radiosensitivity generated by a ruthenium(ii) metallo-intercalator.

Authors:  Martin R Gill; Paul J Jarman; Swagata Halder; Michael G Walker; Hiwa K Saeed; Jim A Thomas; Carl Smythe; Kristijan Ramadan; Katherine A Vallis
Journal:  Chem Sci       Date:  2017-11-16       Impact factor: 9.969

8.  Transcriptomic Analysis of the Activity and Mechanism of Action of a Ruthenium(II)-Based Antimicrobial That Induces Minimal Evolution of Pathogen Resistance.

Authors:  Adam M Varney; Kirsty L Smitten; Jim A Thomas; Samantha McLean
Journal:  ACS Pharmacol Transl Sci       Date:  2020-12-09

9.  Mononuclear ruthenium(ii) theranostic complexes that function as broad-spectrum antimicrobials in therapeutically resistant pathogens through interaction with DNA.

Authors:  Kirsty L Smitten; Eleanor J Thick; Hannah M Southam; Jorge Bernardino de la Serna; Simon J Foster; Jim A Thomas
Journal:  Chem Sci       Date:  2020-07-30       Impact factor: 9.825

10.  Modifying charge and hydrophilicity of simple Ru(II) polypyridyl complexes radically alters biological activities: old complexes, surprising new tricks.

Authors:  Matthew Dickerson; Yang Sun; Brock Howerton; Edith C Glazer
Journal:  Inorg Chem       Date:  2014-09-24       Impact factor: 5.165
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