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Literature DB >> 21433214

A lipase-responsive vehicle using amphipathic polymer synthesized with the lipase as catalyst.

Jun Ge¹, Diannan Lu, Cheng Yang, Zheng Liu.

Abstract

We describe an enzyme-responsive polymeric vehicle, which is of great interest in controlled drug delivery, biosensing, and other related areas. The polymer synthesized using lipase as catalyst in DMSO has a favorable molecular structure that is quickly hydrolyzed by lipase in aqueous phase, and allows a fast release of encapsulated molecules.

Entities: Chemical

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Year: 2011 PMID： 21433214 DOI： 10.1002/marc.201000746

Source DB: PubMed Journal: Macromol Rapid Commun ISSN： 1022-1336 Impact factor: 5.734

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Cited

4 in total

1. Fusion of self-assembling amphipathic oligopeptides with cyclodextrin glycosyltransferase improves 2-O-D-glucopyranosyl-L-ascorbic acid synthesis with soluble starch as the glycosyl donor.

Authors: Ruizhi Han; Jianghua Li; Hyun-dong Shin; Rachel R Chen; Long Liu; Guocheng Du; Jian Chen
Journal: Appl Environ Microbiol Date: 2014-08 Impact factor: 4.792

A lipase-responsive vehicle using amphipathic polymer synthesized with the lipase as catalyst.

1. Fusion of self-assembling amphipathic oligopeptides with cyclodextrin glycosyltransferase improves 2-O-D-glucopyranosyl-L-ascorbic acid synthesis with soluble starch as the glycosyl donor.

2. Drug release from electric-field-responsive nanoparticles.

Review 3. Nanogels Capable of Triggered Release.

4. Fabrication of hydrolase responsive diglycerol based Gemini amphiphiles for dermal drug delivery applications.