Literature DB >> 214326

Studies on the hydrolysis of bradykinin by angiotensin-converting enzyme (kininase II).

F E Dorer, J M Stewart, J W Ryan.   

Abstract

Arg-Pro-Pro-Gly-Phe, the N-terminal pentapeptide of bradykinin, is not an inhibitor of angiotensin-converting enzyme and is not hydrolyzed by the enzyme. Arg-Pro-Pro, the N-terminal tripeptide is a relatively potent (IC50 = 2.3 X 10(6) M) inhibitor but its higher homolog. Gly-Arg-Met-Lys-Arg-Pro-Pro is not an inhibitor of angiotensin-converting enzyme.

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Year:  1978        PMID: 214326     DOI: 10.1007/bf01932334

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  7 in total

1.  Kinetic properties of pulmonary angiotensin-converting enzyme. Hydrolysis of hippurylglycylglycine.

Authors:  F E Dorer; J R Kahn; K E Lentz; M Levine; L T Skeggs
Journal:  Biochim Biophys Acta       Date:  1976-03-11

2.  Catabolism of vasoactive polypeptides by perfused rat liver.

Authors:  D R Borges; E A Limãos; J L Prado; A C Camargo
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1976-10       Impact factor: 3.000

3.  Inhibition of the angiotensin I converting enzyme of the lung by a peptide fragment of bradykinin.

Authors:  G Oshima; E G Erdös
Journal:  Experientia       Date:  1974-07-15

4.  Hydrolysis of bradykinin by angiotensin-converting enzyme.

Authors:  F E Dorer; J R Kahn; K E Lentz; M Levine; L T Skeggs
Journal:  Circ Res       Date:  1974-06       Impact factor: 17.367

5.  Angiotensin-converting enzyme from rabbit pulmonary particles.

Authors:  R L Soffer; R Reza; P R Caldwell
Journal:  Proc Natl Acad Sci U S A       Date:  1974-05       Impact factor: 11.205

6.  Angiotensin I converting enzyme of the lung.

Authors:  R Igic; E G Erdös; H S Yeh; K Sorrells; T Nakajima
Journal:  Circ Res       Date:  1972-09       Impact factor: 17.367

7.  Purification and properties of angiotensin-converting enzyme from hog lung.

Authors:  F E Dorer; J R Kahn; K E Lentz; M Levine; L T Skeggs
Journal:  Circ Res       Date:  1972-09       Impact factor: 17.367

  7 in total

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