Masahiro Toda1, Kanehisa Morimoto, Sei-Ichi Nakamura. 1. Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine, 2-2 Yamada-Oka, 565-0871, Suna, Osaka, Japan.
Abstract
OBJECTIVES: The purpose of this study was to investigate the effect of tomato juice drinking on the antimutagenicity of saliva. METHODS:Subjects were 22 healthy male university students. They were divided into tomato group and control group. The tomato group drank tomato juice for 10 days. The anti-mutagenicity of saliva was measured using the umu test. RESULTS: In the tomato group, there was a significant increase in the inhibiting capacity of saliva on the mutagenicity of AF-2 after tomato juice drinking for 10 days. This increase was, however, temporary. In the control group, there was no such change in the inhibiting capacity of saliva. CONCLUSIONS: These findings suggest the significant effect of tomato juice drinking on the anti-mutagenicity of saliva. In addition, lycopene may have played an important role in its mechanism.
RCT Entities:
OBJECTIVES: The purpose of this study was to investigate the effect of tomato juice drinking on the antimutagenicity of saliva. METHODS: Subjects were 22 healthy male university students. They were divided into tomato group and control group. The tomato group drank tomato juice for 10 days. The anti-mutagenicity of saliva was measured using the umu test. RESULTS: In the tomato group, there was a significant increase in the inhibiting capacity of saliva on the mutagenicity of AF-2 after tomato juice drinking for 10 days. This increase was, however, temporary. In the control group, there was no such change in the inhibiting capacity of saliva. CONCLUSIONS: These findings suggest the significant effect of tomato juice drinking on the anti-mutagenicity of saliva. In addition, lycopene may have played an important role in its mechanism.
Entities:
Keywords:
anti-mutagenicity; human saliva; lycopene; tomato juice drinking; umu test
Authors: E Zuskin; J Mustajbegovic; E N Schachter; B Kanceljak; J Godnic-Cvar; V Sitar-Srebocan Journal: Am J Ind Med Date: 1995-06 Impact factor: 2.214