Literature DB >> 21432323

Methodological issues for a large-scale intervention trial of lifestyle modification: Interim assessment of the high-risk and population strategy for occupational health promotion (HIPOP-OHP) study.

Tomonori Okamura1, Taichiro Tanaka, Toru Takebayashi, Hideaki Nakagawa, Hiroshi Yamato, Katsushi Yoshita, Takashi Kadowaki, Akira Okayama, Hirotsugu Ueshima.   

Abstract

OBJECTIVE: To clarify the methodological issues for the High-risk and population Strategy for Occupational Health Promotion Study (HIPOP-OHP study), which is a 4-year non-randomized control trial, an interim assessment of male participants was performed 3 years after the baseline survey.
METHODS: We had approximately 2,500 and 4,000 participants in the intervention and control groups, respectively. The population measures and prevalence of risk factors at each year, and between the baseline and 4th examinations were compared between the two groups. The personal trends of returning participants who were in the study at the 1(st) and 4(th) examinations were also evaluated.
RESULTS: During the 3 years, an increase in serum HDL cholesterol (2.7 mg/dl), and a reduction in the prevalence of hypertriglycemia detected with fasting blood samples (3.6%) and current smokers (5.4%) were observed in the intervention group. The mean HDL cholesterol level was significantly higher in the intervention group than in the control group at the 4th examination, reversed from the baseline survey. The serum non-HDL cholesterol level was significantly increased only in the control group. There was also a significant increase in the prevalence of hypertriglycemia nad high plasma glucose detected with fasting blood samples in the control group. The return participation rate after 3 years was 72.2% for the intervention group and 74.9% for the control group. The above-mentioned changes for risk factors were mainly due to returning participants at each examination.
CONCLUSION: These interventional methods may be effective in improving overall cardiovascular risk factors in the population. However, the low return participation rate will dilute the effect of the intervention.

Entities:  

Keywords:  cardiovascular risk factor; interim assessment; intervention; population strategy; return participation

Year:  2004        PMID: 21432323      PMCID: PMC2723569          DOI: 10.1007/BF02898092

Source DB:  PubMed          Journal:  Environ Health Prev Med        ISSN: 1342-078X            Impact factor:   3.674


  24 in total

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7.  Stages of change for salt intake and urinary salt excretion: baseline results from the High-Risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) study.

Authors:  Junko Tamaki; Yuriko Kikuchi; Katsushi Yoshita; Toru Takebayashi; Nagako Chiba; Taichiro Tanaka; Tomonori Okamura; Fumiyoshi Kasagi; Junko Minai; Hirotsugu Ueshima
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8.  Effects of a long-term hypertension control program on stroke incidence and prevalence in a rural community in northeastern Japan.

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Authors:  Masakazu Nakamura; Shinichi Sato; Takashi Shimamoto
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  1 in total

1.  Salt reduction in a population for the prevention of hypertension.

Authors:  Hideaki Nakagawa; Katsuyuki Miura
Journal:  Environ Health Prev Med       Date:  2004-07       Impact factor: 3.674

  1 in total

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