Literature DB >> 21432284

Daily lifestyles and anti-mutagenicity of saliva.

Masahiro Toda1, Kanehisa Morimoto, Sei-Ichi Nakamura, Kazuo Hayakawa.   

Abstract

OBJECTIVES: The purpose of this study was to investigate the relation between lifestyle and the antimutagenicity of saliva.
METHODS: Subjects were 52 healthy female university students. The collection of the saliva samples and the lifestyle measurements were carried out for them. The anti-mutagenicity of the saliva was measured using the umu test.
RESULTS: With regard to the lifestyle items, only "nutrient balance" tended to contribute positively to the inhibiting capacity of the saliva on the mutagenicity of AF-2. In addition, there was a significant inverse correlation between the score of 7 other items and the inhibiting capacity of the saliva (r=-0.32; p<0.05). We also found a significant relation between their tea and/or coffee consumption and the inhibiting capacity of the saliva.
CONCLUSIONS: These findings suggest that the inhibiting capacity of saliva worked to decrease mutagen levels that were enhanced by poor lifestyle. In addition, "nutrient balance" may contribute to the inhibiting capacity of the saliva independent of 7 other items. With regard to the tea and/or coffee consumption. further studies should be carried out.

Entities:  

Keywords:  anti-mutagenicity; human saliva; lifestyle; tea and coffee consumption; umu test

Year:  2002        PMID: 21432284      PMCID: PMC2723233          DOI: 10.1007/BF02898060

Source DB:  PubMed          Journal:  Environ Health Prev Med        ISSN: 1342-078X            Impact factor:   3.674


  19 in total

1.  The mutagenicities of alkaloids and N-nitrosoguvacoline from betel quid.

Authors:  C K Wang; C H Peng
Journal:  Mutat Res       Date:  1996-08-08       Impact factor: 2.433

2.  Antimutagenic effect of resveratrol against Trp-P-1.

Authors:  F Uenobe; S Nakamura; M Miyazawa
Journal:  Mutat Res       Date:  1997-02-03       Impact factor: 2.433

3.  The unique correlation between anti-mutagenicity of human saliva and change in body weight.

Authors:  M Toda; K Morimoto; S Nakamura; T Umeda; S Nakaji; K Sugawara
Journal:  Environ Health Prev Med       Date:  2001-07       Impact factor: 3.674

4.  Urinary mutagens and lifestyle factors.

Authors:  K Mure; T Takeshita; T Takeuchi; K Morimoto
Journal:  Prev Med       Date:  1996 Sep-Oct       Impact factor: 4.018

5.  Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test.

Authors:  B N Ames; J Mccann; E Yamasaki
Journal:  Mutat Res       Date:  1975-12       Impact factor: 2.433

6.  Adsorption of pyrolysate mutagens by vegetable fibers.

Authors:  T Kada; M Kato; K Aikawa; S Kiriyama
Journal:  Mutat Res       Date:  1984 Nov-Dec       Impact factor: 2.433

7.  A comparison of whole mouth resting and stimulated salivary measurement procedures.

Authors:  M Navazesh; C M Christensen
Journal:  J Dent Res       Date:  1982-10       Impact factor: 6.116

8.  SOS-inducing activity of chemical carcinogens and mutagens in Salmonella typhimurium TA1535/pSK1002: examination with 151 chemicals.

Authors:  S I Nakamura; Y Oda; T Shimada; I Oki; K Sugimoto
Journal:  Mutat Res       Date:  1987-12       Impact factor: 2.433

9.  Mutagenicity and carcinogenicity of masheri, a pyrolysed tobacco product, and its content of tobacco-specific nitrosamines.

Authors:  S V Bhide; J Kulkarni; U J Nair; B Spiegelhalder; R Preussmann
Journal:  IARC Sci Publ       Date:  1987

10.  [The anti-mutagenic effects of human saliva investigated by umu-test. Part 1. Effects of filtration and storage at low temperatures].

Authors:  M Okada; S Nakamura; K Miura; K Morimoto
Journal:  Nihon Eiseigaku Zasshi       Date:  1989-12
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  1 in total

1.  A further note on the sampling device for the anti-mutagenicity of saliva.

Authors:  Masahiro Toda; Kanehisa Morimoto; Sei-Ichi Nakamura; Kazuo Hayakawa
Journal:  Environ Health Prev Med       Date:  2002-04       Impact factor: 3.674

  1 in total

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