Literature DB >> 21431974

Endovascular treatment of acute arterial hemorrhage in trauma patients using ethylene vinyl alcohol copolymer (Onyx).

R Müller-Wille1, P Heiss, T Herold, E M Jung, A G Schreyer, O W Hamer, J Rennert, P Hoffstetter, C Stroszczynski, N Zorger.   

Abstract

PURPOSE: This study was designed to determine the feasibility and efficacy of endovascular embolization with liquid embolic agent ethylene vinyl alcohol copolymer (Onyx) in patients with acute traumatic arterial bleeding.
METHODS: This is a retrospective review of 13 patients (9 men and 4 women; mean age 45 years) with severe trauma who underwent embolotherapy using Onyx from November 2003 to February 2009. Bleeding was located in the pelvis (5 patients), kidney (3 patients), mesenteric region (2 patients), retroperitoneal space (2 patients), neck (1 patient), and thigh (1 patient). In three cases (23.1%), Onyx was used in conjunction with coils. We evaluate the technical and clinical success, procedural and embolization time, occurrence of rebleeding, and embolotherapy-related complications, such as necrosis or migration of Onyx into nontarget vessels.
RESULTS: In all patients, embolotherapy was technically and clinically successful on the first attempt. Control of bleeding could be reached with a mean time of 19 (range, 4-63) min after correct placement of the microcatheter in the feeding artery. No recurrent bleeding was detected. No unintended necrosis or migration of Onyx into a nontarget region was observed. During the follow-up period, three patients (23.1%) died due to severe intracranial hemorrhage, cardiac arrest, and sepsis.
CONCLUSIONS: Transcatheter embolization with new liquid embolic agent Onyx is technically feasible and effective in trauma patients with acute arterial hemorrhage.

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Year:  2011        PMID: 21431974     DOI: 10.1007/s00270-011-0134-x

Source DB:  PubMed          Journal:  Cardiovasc Intervent Radiol        ISSN: 0174-1551            Impact factor:   2.740


  4 in total

1.  Embolization of traumatic and non-traumatic peripheral vascular lesions with Onyx.

Authors:  Renato Regine; Francesco Palmieri; Michele De Siero; Antonio Rescigno; Vincenzo Sica; Raffaele Cantarela; Vincenzo Villari
Journal:  Interv Med Appl Sci       Date:  2015-03-20

Review 2.  The role of interventional radiology in abdominopelvic trauma.

Authors:  Anna Maria Ierardi; Ejona Duka; Natalie Lucchina; Chiara Floridi; Alessandro De Martino; Daniela Donat; Federico Fontana; Gianpaolo Carrafiello
Journal:  Br J Radiol       Date:  2016-01-05       Impact factor: 3.039

3.  Multidisciplinary Management of Low-velocity Nonmissile Penetrating Head Injuries.

Authors:  Michael Young; Matthew Putty; Megan M Finneran; Ryan Johnson; Keith Schaible; Hamad Farhat
Journal:  Cureus       Date:  2020-03-24

4.  Embolization with ethylene vinyl alcohol copolymer (Onyx®) for peripheral hemostatic and non-hemostatic applications: a feasibility and safety study.

Authors:  Romaric Né; Olivier Chevallier; Nicolas Falvo; Olivier Facy; Pierre-Emmanuel Berthod; Christophe Galland; Sophie Gehin; Marco Midulla; Romaric Loffroy
Journal:  Quant Imaging Med Surg       Date:  2018-04
  4 in total

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