Literature DB >> 2143181

Asperfuran, a novel antifungal metabolite from Aspergillus oryzae.

W Pfefferle1, H Anke, M Bross, B Steffan, R Vianden, W Steglich.   

Abstract

Asperfuran is a novel antifungal dihydrobenzofuran derivative produced by a strain of Aspergillus oryzae. Asperfuran weakly inhibited chitin synthase from Coprinus cinereus. This inhibition could be abolished by the addition of egg lecithin. In the agar diffusion assay asperfuran induced morphological changes in Mucor miehei at very low concentrations (20 ng/disc) while growth was only partly inhibited. In HeLa S3 and L1210 cells it showed weak cytotoxicity, the IC50 was 25 micrograms/ml.

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Year:  1990        PMID： 2143181     DOI： 10.7164/antibiotics.43.648

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  6 in total

1.  Taxonomy of Aspergillus section Flavi and their production of aflatoxins, ochratoxins and other mycotoxins.

Authors:  J C Frisvad; V Hubka; C N Ezekiel; S-B Hong; A Nováková; A J Chen; M Arzanlou; T O Larsen; F Sklenář; W Mahakarnchanakul; R A Samson; J Houbraken
Journal:  Stud Mycol       Date:  2018-07-31       Impact factor: 16.097

2.  Comparative Chemistry of Aspergillus oryzae (RIB40) and A. flavus (NRRL 3357).

Authors:  Christian Rank; Marie Louise Klejnstrup; Lene Maj Petersen; Sara Kildgaard; Jens Christian Frisvad; Charlotte Held Gotfredsen; Thomas Ostenfeld Larsen
Journal:  Metabolites       Date:  2012-01-05

3.  First evidence of mineralization of petroleum asphaltenes by a strain of Neosartorya fischeri.

Authors:  Cristina Uribe-Alvarez; Marcela Ayala; Lucia Perezgasga; Leopoldo Naranjo; Héctor Urbina; Rafael Vazquez-Duhalt
Journal:  Microb Biotechnol       Date:  2011-05-30       Impact factor: 5.813

4.  A new benzofuran glycoside and indole alkaloids from a sponge-associated rare actinomycete, Amycolatopsis sp.

Authors:  Yun Kwon; Seong-Hwan Kim; Yoonho Shin; Munhyung Bae; Byung-Yong Kim; Sang Kook Lee; Ki-Bong Oh; Jongheon Shin; Dong-Chan Oh
Journal:  Mar Drugs       Date:  2014-04-22       Impact factor: 5.118

Review 5.  Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and Trichoderma reesei.

Authors:  Jens C Frisvad; Lars L H Møller; Thomas O Larsen; Ravi Kumar; José Arnau
Journal:  Appl Microbiol Biotechnol       Date:  2018-10-06       Impact factor: 4.813

6.  Pigmentosins from Gibellula sp. as antibiofilm agents and a new glycosylated asperfuran from Cordyceps javanica.

Authors:  Soleiman E Helaly; Wilawan Kuephadungphan; Patima Phainuphong; Mahmoud A A Ibrahim; Kanoksri Tasanathai; Suchada Mongkolsamrit; Janet Jennifer Luangsa-Ard; Souwalak Phongpaichit; Vatcharin Rukachaisirikul; Marc Stadler
Journal:  Beilstein J Org Chem       Date:  2019-12-16       Impact factor: 2.883
  6 in total

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