| Literature DB >> 21431448 |
G Bens1, R Kerdraon, J-J De Kyvon, E Estève.
Abstract
Sinus histiocytosis with massive lymphadenopathy (SHML) is generally characterized by severe illness and massive cervical lymphadenopathy. Sinus histiocytosis limited to the skin is now recognized as a rare distinct entity called cutaneous Rosai-Dorfman disease (CRD). We report CRD in a 57-year-old male patient presenting with disseminated firm red-brown papules. Histology revealed a dermal infiltrate with CD1a-, CD68+, S100+ multinuclear giant cells. Some of these histiocytes showed hemophagocytosis (emperipolesis). We achieved a good therapeutic result with topical clobetasol propionate.Entities:
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Year: 2011 PMID: 21431448 DOI: 10.1007/s00105-011-2140-y
Source DB: PubMed Journal: Hautarzt ISSN: 0017-8470 Impact factor: 0.751