Literature DB >> 21429515

Increasing severity of pectus excavatum is associated with reduced pulmonary function.

M Louise Lawson1, Robert B Mellins, James F Paulson, Robert C Shamberger, Keith Oldham, Richard G Azizkhan, Andre V Hebra, Donald Nuss, Michael J Goretsky, Ronald J Sharp, George W Holcomb, Walton K T Shim, Stephen M Megison, R Lawrence Moss, Annie H Fecteau, Paul M Colombani, Alan B Moskowitz, Joshua Hill, Robert E Kelly.   

Abstract

OBJECTIVE: To determine whether pulmonary function decreases as a function of severity of pectus excavatum, and whether reduced function is restrictive or obstructive in nature in a large multicenter study. STUDY
DESIGN: We evaluated preoperative spirometry data in 310 patients and lung volumes in 218 patients aged 6 to 21 years at 11 North American centers. We modeled the impact of the severity of deformity (based on the Haller index) on pulmonary function.
RESULTS: The percentages of patients with abnormal forced vital capacity (FVC), forced expiratory volume in 1 second (FEV(1)), forced expiratory flow from 25% exhalation to 75% exhalation, and total lung capacity findings increased with increasing Haller index score. Less than 2% of patients demonstrated an obstructive pattern (FEV(1)/FVC <67%), and 14.5% demonstrated a restrictive pattern (FVC and FEV(1) <80% predicted; FEV(1)/FVC >80%). Patients with a Haller index of 7 are >4 times more likely to have an FVC of ≤80% than those with a Haller index of 4, and are also 4 times more likely to exhibit a restrictive pulmonary pattern.
CONCLUSIONS: Among patients presenting for surgical repair of pectus excavatum, those with more severe deformities have a much higher likelihood of decreased pulmonary function with a restrictive pulmonary pattern.
Copyright © 2011 Mosby, Inc. All rights reserved.

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Year:  2011        PMID: 21429515     DOI: 10.1016/j.jpeds.2011.01.065

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  17 in total

Review 1.  Anaesthesia for the surgical correction of chest wall deformities.

Authors:  T Ghafoor; M Edsell; I Hunt
Journal:  BJA Educ       Date:  2020-07-01

Review 2.  Ravitch versus Nuss procedure for pectus excavatum: systematic review and meta-analysis.

Authors:  Aran Kanagaratnam; Steven Phan; Vakhtang Tchantchaleishvili; Kevin Phan
Journal:  Ann Cardiothorac Surg       Date:  2016-09

3.  Diminished pulmonary function in pectus excavatum: from denying the problem to finding the mechanism.

Authors:  Robert E Kelly; Robert J Obermeyer; Donald Nuss
Journal:  Ann Cardiothorac Surg       Date:  2016-09

4.  Pulmonary function in children with Pectus excavatum and post-operative changes after nuss procedure.

Authors:  Hisako Kuyama; Sadashige Uemura; Atsushi Yoshida; Mayumi Yamamoto
Journal:  Pediatr Surg Int       Date:  2018-08-06       Impact factor: 1.827

5.  Pectus excavatum severity underestimated due to lack of objective measures in radiological reports.

Authors:  Hans Kragten; Paul Höppener; Albert Gielis; Machiel de Booij
Journal:  BMJ Case Rep       Date:  2016-05-23

6.  A comparison between laryngeal mask airway and endotracheal intubation for anaesthesia in adult patients undergoing NUSS procedure.

Authors:  Songsong Mao; Xiaojun Du; Jue Ma; Guangyan Zhang; Jianxiu Cui
Journal:  J Thorac Dis       Date:  2018-06       Impact factor: 2.895

7.  Objective effect manifestation of pectus excavatum on load-stressed pulmonary function testing: a case report.

Authors:  Jason Yongsheng Chan; Wei Liang Huang
Journal:  J Med Case Rep       Date:  2011-12-21

8.  Pulmonary function before and after the Nuss procedure in adolescents with pectus excavatum: correlation with morphological subtypes.

Authors:  Jin Yong Jeong; Joong Hyun Ahn; Sang Yong Kim; Yoon Hong Chun; Kyungdo Han; Sung Bo Sim; Keon Hyon Jo
Journal:  J Cardiothorac Surg       Date:  2015-03-22       Impact factor: 1.637

Review 9.  Systematic review of surgical treatment techniques for adult and pediatric patients with pectus excavatum.

Authors:  William Rainey Johnson; David Fedor; Sunil Singhal
Journal:  J Cardiothorac Surg       Date:  2014-02-07       Impact factor: 1.637

10.  Lung density analysis using quantitative computed tomography in children with pectus excavatum.

Authors:  Fatma C Sarioglu; Naciye S Gezer; Huseyin Odaman; Orkun Sarioglu; Oktay Ulusoy; Oguz Ates; Handan Guleryuz
Journal:  Pol J Radiol       Date:  2021-06-22
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