Literature DB >> 21428822

Enzyme-therapy approaches for the treatment of drug overdose and addiction.

Fang Zheng1, Chang-Guo Zhan.   

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Year:  2011        PMID： 21428822      PMCID： PMC4365907          DOI： 10.4155/fmc.10.275

Source DB:  PubMed          Journal:  Future Med Chem        ISSN： 1756-8919            Impact factor:   3.808


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  43 in total

1.  Addiction as a computational process gone awry.

Authors:  A David Redish
Journal:  Science       Date:  2004-12-10       Impact factor: 47.728

2.  Cocaine esterase prevents cocaine-induced toxicity and the ongoing intravenous self-administration of cocaine in rats.

Authors:  Gregory T Collins; Remy L Brim; Diwahar Narasimhan; Mei-Chuan Ko; Roger K Sunahara; Chang-Guo Zhan; James H Woods
Journal:  J Pharmacol Exp Ther       Date:  2009-08-26       Impact factor: 4.030

3.  Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase.

Authors:  Ziva D Cooper; Diwahar Narasimhan; Roger K Sunahara; Pawel Mierzejewski; Emily M Jutkiewicz; Nicholas A Larsen; Ian A Wilson; Donald W Landry; James H Woods
Journal:  Mol Pharmacol       Date:  2006-09-12       Impact factor: 4.436

4.  Catalytic mechanism and energy barriers for butyrylcholinesterase-catalyzed hydrolysis of cocaine.

Authors:  Chang-Guo Zhan; Daquan Gao
Journal:  Biophys J       Date:  2005-12       Impact factor: 4.033

Review 5.  Anti-cocaine vaccine development.

Authors:  Berma M Kinsey; Thomas R Kosten; Frank M Orson
Journal:  Expert Rev Vaccines       Date:  2010-09       Impact factor: 5.217

6.  Incentive learning underlying cocaine-seeking requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons.

Authors:  Martin Novak; Briac Halbout; Eoin C O'Connor; Jan Rodriguez Parkitna; Tian Su; Minqiang Chai; Hans S Crombag; Ainhoa Bilbao; Rainer Spanagel; David N Stephens; Günther Schütz; David Engblom
Journal:  J Neurosci       Date:  2010-09-08       Impact factor: 6.167

7.  Fundamental reaction mechanism for cocaine hydrolysis in human butyrylcholinesterase.

Authors:  Chang-Guo Zhan; Fang Zheng; Donald W Landry
Journal:  J Am Chem Soc       Date:  2003-03-05       Impact factor: 15.419

Review 8.  Rational design of an enzyme mutant for anti-cocaine therapeutics.

Authors:  Fang Zheng; Chang-Guo Zhan
Journal:  J Comput Aided Mol Des       Date:  2007-11-08       Impact factor: 3.686

9.  Thermostable variants of cocaine esterase for long-time protection against cocaine toxicity.

Authors:  Daquan Gao; Diwahar L Narasimhan; Joanne Macdonald; Remy Brim; Mei-Chuan Ko; Donald W Landry; James H Woods; Roger K Sunahara; Chang-Guo Zhan
Journal:  Mol Pharmacol       Date:  2008-11-05       Impact factor: 4.436

10.  Mechanism for cocaine blocking the transport of dopamine: insights from molecular modeling and dynamics simulations.

Authors:  Xiaoqin Huang; Howard H Gu; Chang-Guo Zhan
Journal:  J Phys Chem B       Date:  2009-11-12       Impact factor: 2.991
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  17 in total

1.  Catalytic Reaction Mechanism for Drug Metabolism in Human Carboxylesterase-1: Cocaine Hydrolysis Pathway.

Authors:  Jianzhuang Yao; Xiabin Chen; Fang Zheng; Chang-Guo Zhan
Journal:  Mol Pharm       Date:  2018-08-10       Impact factor: 4.939

2.  Bio-activation of 4-alkyl analogs of 1,4-dihydropyridine mediated by cytochrome P450 enzymes.

Authors:  Xiao-Xi Li; Xiaoqian Zhang; Qing-Chuan Zheng; Yong Wang
Journal:  J Biol Inorg Chem       Date:  2015-03-18       Impact factor: 3.358

3.  Catalytic activities of cocaine hydrolases against the most toxic cocaine metabolite norcocaethylene.

Authors:  Xirong Zheng; Xiabin Chen; Ting Zhang; Max Zhan; Chang-Guo Zhan; Fang Zheng
Journal:  Org Biomol Chem       Date:  2020-03-11       Impact factor: 3.876

4.  A plant-derived cocaine hydrolase prevents cocaine overdose lethality and attenuates cocaine-induced drug seeking behavior.

Authors:  Katherine E Larrimore; Latha Kannan; R Player Kendle; Tameem Jamal; Matthew Barcus; Kathryn Stefanko; Jacquelyn Kilbourne; Stephen Brimijoin; Chang-Guo Zhan; Janet Neisewander; Tsafrir S Mor
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2020-05-06       Impact factor: 5.067

Review 5.  Epigenetics: a link between addiction and social environment.

Authors:  Duyilemi C Ajonijebu; Oualid Abboussi; Vivienne A Russell; Musa V Mabandla; William M U Daniels
Journal:  Cell Mol Life Sci       Date:  2017-03-02       Impact factor: 9.261

6.  Reaction Pathway for Cocaine Hydrolase-Catalyzed Hydrolysis of (+)-Cocaine.

Authors:  Yuan Yao; Junjun Liu; Fang Zheng; Chang-Guo Zhan
Journal:  Theor Chem Acc       Date:  2015-12-28       Impact factor: 1.702

7.  Development of Fc-Fused Cocaine Hydrolase for Cocaine Addiction Treatment: Catalytic and Pharmacokinetic Properties.

Authors:  Xiabin Chen; Jing Deng; Wenpeng Cui; Shurong Hou; Jinling Zhang; Xirong Zheng; Xin Ding; Huimei Wei; Ziyuan Zhou; Kyungbo Kim; Chang-Guo Zhan; Fang Zheng
Journal:  AAPS J       Date:  2018-03-19       Impact factor: 4.009

8.  Catalytic activities of a cocaine hydrolase engineered from human butyrylcholinesterase against (+)- and (-)-cocaine.

Authors:  Liu Xue; Shurong Hou; Wenchao Yang; Lei Fang; Fang Zheng; Chang-Guo Zhan
Journal:  Chem Biol Interact       Date:  2012-08-11       Impact factor: 5.192

9.  Structure-Based Design and Discovery of a Long-Acting Cocaine Hydrolase Mutant with Improved Binding Affinity to Neonatal Fc Receptor for Treatment of Cocaine Abuse.

Authors:  Fang Zheng; Xiabin Chen; Kyungbo Kim; Ting Zhang; Haifeng Huang; Shuo Zhou; Jinling Zhang; Zhenyu Jin; Chang-Guo Zhan
Journal:  AAPS J       Date:  2020-03-18       Impact factor: 4.009

10.  Preparation and in vivo characterization of a cocaine hydrolase engineered from human butyrylcholinesterase for metabolizing cocaine.

Authors:  Liu Xue; Shurong Hou; Min Tong; Lei Fang; Xiabin Chen; Zhenyu Jin; Hsin-Hsiung Tai; Fang Zheng; Chang-Guo Zhan
Journal:  Biochem J       Date:  2013-08-01       Impact factor: 3.857
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