Literature DB >> 21428820

New hope in the fight against malaria?

Tiago Rodrigues, Rui Moreira, Francisca Lopes.   

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Year:  2011        PMID： 21428820     DOI： 10.4155/fmc.10.274

Source DB:  PubMed          Journal:  Future Med Chem        ISSN： 1756-8919            Impact factor:   3.808


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  2 in total

1.  Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitro.

Authors:  Janina Preuss; Patrick Maloney; Satyamaheshwar Peddibhotla; Michael P Hedrick; Paul Hershberger; Palak Gosalia; Monika Milewski; Yujie Linda Li; Eliot Sugarman; Becky Hood; Eigo Suyama; Kevin Nguyen; Stefan Vasile; Eduard Sergienko; Arianna Mangravita-Novo; Michael Vicchiarelli; Danielle McAnally; Layton H Smith; Gregory P Roth; Jena Diwan; Thomas D Y Chung; Esther Jortzik; Stefan Rahlfs; Katja Becker; Anthony B Pinkerton; Lars Bode
Journal:  J Med Chem       Date:  2012-08-06       Impact factor: 7.446

2.  Synthesis, Biological Evaluation, and Molecular Modeling Studies of Chiral Chloroquine Analogues as Antimalarial Agents.

Authors:  Srinivasarao Kondaparla; Utsab Debnath; Awakash Soni; Vasantha Rao Dola; Manish Sinha; Kumkum Srivastava; Sunil K Puri; Seturam B Katti
Journal:  Antimicrob Agents Chemother       Date:  2018-11-26       Impact factor: 5.191
  2 in total

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