Literature DB >> 21427639

Prevalence and correlates of generalized anxiety disorder in a national sample of older adults.

Corey S Mackenzie1, Kristin Reynolds, Kee-Lee Chou, Jina Pagura, Jitender Sareen.   

Abstract

OBJECTIVES: The objectives of this study are to provide current estimates of the prevalence and correlates of generalized anxiety disorder (GAD).
METHODS: The authors used Wave 2 data from the National Epidemiologic Survey on Alcohol and Related Conditions, which included 12,312 adults 55+ and older. In addition to examining the prevalence of GAD in the past year, this study explored psychiatric and medical comorbidity, health-related quality of life, and rates of help-seeking and self-medication.
RESULTS: The past-year prevalence of GAD in this sample was 2.80%, although only 0.53% had GAD without Axis I or II comorbidity. The majority of individuals with GAD had mood or other anxiety disorders, and approximately one quarter had a personality disorder. Individuals with GAD were also more likely to have various chronic health problems although these associations disappeared after controlling for psychiatric comorbidity. Health-related quality of life was reduced among older adults with GAD, even after controlling for health conditions and comorbid major depression. Finally, only 18% of those without and 28.3% with comorbid Axis I disorders sought professional help for GAD in the past year. Self-medication for symptom relief was rare (7.2%).
CONCLUSIONS: GAD is a common and disabling disorder in later life that is highly comorbid with mood, anxiety, and personality disorders; psychiatric comorbidity is associated with an increased risk of medical conditions in this population. Considering that late-life GAD is associated with impaired quality of life but low levels of professional help-seeking increased effort is needed to help individuals with this disorder to access effective treatments.

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Mesh:

Year:  2011        PMID: 21427639     DOI: 10.1097/JGP.0b013e318202bc62

Source DB:  PubMed          Journal:  Am J Geriatr Psychiatry        ISSN: 1064-7481            Impact factor:   4.105


  25 in total

1.  Disorder-specific mental health service use for mood and anxiety disorders: associations with age, sex, and psychiatric comorbidity.

Authors:  Corey S Mackenzie; Kristin Reynolds; John Cairney; David L Streiner; Jitender Sareen
Journal:  Depress Anxiety       Date:  2011-11-07       Impact factor: 6.505

2.  Anxiety disorders: new developments in old age.

Authors:  Eric J Lenze; Julie Loebach Wetherell
Journal:  Am J Geriatr Psychiatry       Date:  2011-04       Impact factor: 4.105

3.  Use of potentially inappropriate medications among ambulatory home-dwelling elderly patients with dementia: A review of the literature.

Authors:  Tejal Patel; Karen Slonim; Linda Lee
Journal:  Can Pharm J (Ott)       Date:  2017-05-01

4.  Prevalence and predictors of persistent versus remitting mood, anxiety, and substance disorders in a national sample of older adults.

Authors:  Corey S Mackenzie; Renée El-Gabalawy; Kee-Lee Chou; Jitender Sareen
Journal:  Am J Geriatr Psychiatry       Date:  2013-06-22       Impact factor: 4.105

5.  Joint trajectories of cigarette smoking and depressive symptoms from the mid-20s to the mid-30s predicting generalized anxiety disorder.

Authors:  Jung Yeon Lee; Judith S Brook; Stephen J Finch; Mario De La Rosa; David W Brook
Journal:  J Addict Dis       Date:  2017-03-10

Review 6.  The National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) Waves 1 and 2: review and summary of findings.

Authors:  Deborah S Hasin; Bridget F Grant
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2015-07-26       Impact factor: 4.328

Review 7.  Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders.

Authors:  Martin A Katzman; Pierre Bleau; Pierre Blier; Pratap Chokka; Kevin Kjernisted; Michael Van Ameringen; Martin M Antony; Stéphane Bouchard; Alain Brunet; Martine Flament; Sophie Grigoriadis; Sandra Mendlowitz; Kieron O'Connor; Kiran Rabheru; Peggy M A Richter; Melisa Robichaud; John R Walker
Journal:  BMC Psychiatry       Date:  2014-07-02       Impact factor: 3.630

Review 8.  Application of a cognitive neuroscience perspective of cognitive control to late-life anxiety.

Authors:  Sherry A Beaudreau; Anna MacKay-Brandt; Jeremy Reynolds
Journal:  J Anxiety Disord       Date:  2013-03-22

9.  Effects of Telephone-Delivered Cognitive-Behavioral Therapy and Nondirective Supportive Therapy on Sleep, Health-Related Quality of Life, and Disability.

Authors:  Gretchen A Brenes; Suzanne C Danhauer; Mary F Lyles; Andrea Anderson; Michael E Miller
Journal:  Am J Geriatr Psychiatry       Date:  2016-04-15       Impact factor: 4.105

10.  Two weeks of predatory stress induces anxiety-like behavior with co-morbid depressive-like behavior in adult male mice.

Authors:  Jillybeth Burgado; Constance S Harrell; Darrell Eacret; Renuka Reddy; Christopher J Barnum; Malú G Tansey; Andrew H Miller; Huichen Wang; Gretchen N Neigh
Journal:  Behav Brain Res       Date:  2014-09-06       Impact factor: 3.332

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