Literature DB >> 21427404

Improved growth and anemia in HIV-infected African children taking cotrimoxazole prophylaxis.

Andrew Prendergast1, A Sarah Walker, Veronica Mulenga, Chifumbe Chintu, Diana M Gibb.   

Abstract

The impact of cotrimoxazole (CTX) on growth and/or anemia was investigated in 541 human immunodeficiency virus-infected, antiretroviral therapy-naive Zambian children enrolled in the Children with HIV Antibiotic Prophylaxis trial. Compared with children randomized to receive placebo, children randomized to receive CTX had slower decreases in weight-for-age (P=.04) and height-for-age (P=.01), and greater increase in hemoglobin level (P=.01). These findings argue for expanded early CTX use.
© The Author 2011. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved.

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Year:  2011        PMID： 21427404     DOI： 10.1093/cid/cir029

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  23 in total

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