Literature DB >> 21426466

Scurvy: historically a plague of the sailor that remains a consideration in the modern intensive care unit.

A D Holley1, E Osland, J Barnes, A Krishnan, J F Fraser.   

Abstract

We report the case of the case of a 56 year old female with sepsis on a background of rheumatoid arthritis and steroid use manifesting with overt clinical features of scurvy. Ascorbic acid assays were able to demonstrate severe deficiency and confirm a diagnosis of scurvy. Clinical resolution of signs and symptoms following commencement of vitamin C replacement was rapid. The intensivist and dietitian need to consider this diagnosis even in the first world setting, particularly in the presence of sepsis, inflammatory conditions, steroid use and importantly malnutrition.
© 2011 The Authors. Internal Medicine Journal © 2011 Royal Australasian College of Physicians.

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Year:  2011        PMID: 21426466     DOI: 10.1111/j.1445-5994.2010.02413.x

Source DB:  PubMed          Journal:  Intern Med J        ISSN: 1444-0903            Impact factor:   2.048


  6 in total

1.  Impure placebo is a useless concept.

Authors:  Pekka Louhiala; Harri Hemilä; Raimo Puustinen
Journal:  Theor Med Bioeth       Date:  2015-08

2.  Vitamin C deficiency in an anticoagulated patient.

Authors:  George M Yousef; Lynne J Goebel
Journal:  J Gen Intern Med       Date:  2012-11-29       Impact factor: 5.128

3.  Effect of high-dose Ascorbic acid on vasopressor's requirement in septic shock.

Authors:  Mohadeseh Hosseini Zabet; Mostafa Mohammadi; Masoud Ramezani; Hossein Khalili
Journal:  J Res Pharm Pract       Date:  2016 Apr-Jun

Review 4.  Vitamin C and Infections.

Authors:  Harri Hemilä
Journal:  Nutrients       Date:  2017-03-29       Impact factor: 5.717

Review 5.  The role of vitamin C in the treatment of pain: new insights.

Authors:  Anitra C Carr; Cate McCall
Journal:  J Transl Med       Date:  2017-04-14       Impact factor: 5.531

6.  Ascorbate-dependent vasopressor synthesis: a rationale for vitamin C administration in severe sepsis and septic shock?

Authors:  Anitra C Carr; Geoffrey M Shaw; Alpha A Fowler; Ramesh Natarajan
Journal:  Crit Care       Date:  2015-11-27       Impact factor: 9.097

  6 in total

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