OBJECTIVE: To examine the social cognitive vulnerabilities mediating delusion formation in children presenting with hallucinatory experiences. METHOD: A sample of 259 12- and 13-year-old children, from a baseline case-control sample of children with and without auditory hallucinations (AH), were re-assessed after 5 years for presence of AH. Presence of delusions and theory of mind (ToM) were also assessed, to examine the hypothesized moderating role of ToM in delusion formation in children hearing voices. RESULTS: In children with AH at age 7-8 and/or 12-13 years, the risk of delusion formation was significantly higher (P interaction = 0.027) in those with lower ToM skills (OR = 4.3, 95% CI 1.9-9.9, P = 0.000), compared to those with higher ToM skills (OR 1.6, 95% CI 0.7-3.7, P = 0.26), independently from secondary school level. CONCLUSION: The results suggest that better mentalizing abilities confer protection against delusion formation in children experiencing perceptual anomalies, not reducible to general cognitive ability.
OBJECTIVE: To examine the social cognitive vulnerabilities mediating delusion formation in children presenting with hallucinatory experiences. METHOD: A sample of 259 12- and 13-year-old children, from a baseline case-control sample of children with and without auditory hallucinations (AH), were re-assessed after 5 years for presence of AH. Presence of delusions and theory of mind (ToM) were also assessed, to examine the hypothesized moderating role of ToM in delusion formation in children hearing voices. RESULTS: In children with AH at age 7-8 and/or 12-13 years, the risk of delusion formation was significantly higher (P interaction = 0.027) in those with lower ToM skills (OR = 4.3, 95% CI 1.9-9.9, P = 0.000), compared to those with higher ToM skills (OR 1.6, 95% CI 0.7-3.7, P = 0.26), independently from secondary school level. CONCLUSION: The results suggest that better mentalizing abilities confer protection against delusion formation in children experiencing perceptual anomalies, not reducible to general cognitive ability.
Authors: Lars Clemmensen; Jim van Os; Anne Mette Skovgaard; Mette Væver; Els M A Blijd-Hoogewys; Agna A Bartels-Velthuis; Pia Jeppesen Journal: PLoS One Date: 2014-11-14 Impact factor: 3.240
Authors: Martin Debbané; George Salaminios; Patrick Luyten; Deborah Badoud; Marco Armando; Alessandra Solida Tozzi; Peter Fonagy; Benjamin K Brent Journal: Front Hum Neurosci Date: 2016-08-22 Impact factor: 3.169
Authors: Lars Clemmensen; Agna A Bartels-Velthuis; Rókur Av F Jespersen; Jim van Os; Els M A Blijd-Hoogewys; Lise Ankerstrøm; Mette Væver; Peter F Daniel; Marjan Drukker; Pia Jeppesen; Jens R M Jepsen Journal: Front Psychol Date: 2016-03-08
Authors: Laura A Steenhuis; Gerdina H M Pijnenborg; Jim van Os; André Aleman; Maaike H Nauta; Agna A Bartels-Velthuis Journal: PLoS One Date: 2019-02-28 Impact factor: 3.240
Authors: Renaud Jardri; Agna A Bartels-Velthuis; Martin Debbané; Jack A Jenner; Ian Kelleher; Yves Dauvilliers; Giuseppe Plazzi; Morgane Demeulemeester; Christopher N David; Judith Rapoport; Dries Dobbelaere; Sandra Escher; Charles Fernyhough Journal: Schizophr Bull Date: 2014-07 Impact factor: 9.306
Authors: Lisa R Steenkamp; Henning Tiemeier; Laura M E Blanken; Manon H J Hillegers; Steven A Kushner; Koen Bolhuis Journal: Br J Psychiatry Date: 2021-12 Impact factor: 9.319