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Literature DB >> 21425242

Enhancement of imaging depth in turbid media using a wide area detector.

Viera Crosignani¹, Alexander S Dvornikov, Enrico Gratton.

Abstract

The depth of two-photon fluorescence imaging in turbid media can be significantly enhanced by the use of the here described fluorescence detection method that allows to efficiently collect scattered fluorescence photons from a wide area of the turbid sample. By using this detector we were able to perform imaging of turbid samples, simulating brain tissue, at depths up to 3 mm, where the two-photon induced fluorescence signal is too weak to be detected by means used in conventional two-photon microscopy.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：
Gelatin
Agar
Silicon

Year: 2011 PMID： 21425242 PMCID： PMC4245154 DOI： 10.1002/jbio.201100001

Source DB: PubMed Journal: J Biophotonics ISSN： 1864-063X Impact factor: 3.207

22 in total

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Review 3. Fiber-optic fluorescence imaging.

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5. Influence of optical properties on two-photon fluorescence imaging in turbid samples.

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6. Compact non-contact total emission detection for in vivo multiphoton excitation microscopy.

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