Literature DB >> 21423161

Screening: Low-fat worms on drugs.

Bridget K Wagner1.   

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Year:  2011        PMID: 21423161     DOI: 10.1038/nchembio.540

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN: 1552-4450            Impact factor:   15.040


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  10 in total

1.  Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome.

Authors:  Barbara Cool; Bradley Zinker; William Chiou; Lemma Kifle; Ning Cao; Matthew Perham; Robert Dickinson; Andrew Adler; Gerard Gagne; Rajesh Iyengar; Gang Zhao; Kennan Marsh; Philip Kym; Paul Jung; Heidi S Camp; Ernst Frevert
Journal:  Cell Metab       Date:  2006-06       Impact factor: 27.287

2.  Identification of novel antimicrobials using a live-animal infection model.

Authors:  Terence I Moy; Anthony R Ball; Zafia Anklesaria; Gabriele Casadei; Kim Lewis; Frederick M Ausubel
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-26       Impact factor: 11.205

3.  A small-molecule screen in C. elegans yields a new calcium channel antagonist.

Authors:  Trevor C Y Kwok; Nicole Ricker; Regina Fraser; Allen W Chan; Andrew Burns; Elise F Stanley; Peter McCourt; Sean R Cutler; Peter J Roy
Journal:  Nature       Date:  2006-05-04       Impact factor: 49.962

4.  C elegans: a model for exploring the genetics of fat storage.

Authors:  Renée M McKay; James P McKay; Leon Avery; Jonathan M Graff
Journal:  Dev Cell       Date:  2003-01       Impact factor: 12.270

5.  Serotonin regulates C. elegans fat and feeding through independent molecular mechanisms.

Authors:  Supriya Srinivasan; Leila Sadegh; Ida C Elle; Anne G L Christensen; Nils J Faergeman; Kaveh Ashrafi
Journal:  Cell Metab       Date:  2008-06       Impact factor: 27.287

6.  Polygenic control of Caenorhabditis elegans fat storage.

Authors:  Ho Yi Mak; Laura S Nelson; Michael Basson; Carl D Johnson; Gary Ruvkun
Journal:  Nat Genet       Date:  2006-02-05       Impact factor: 38.330

7.  Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation.

Authors:  Jason Rihel; David A Prober; Anthony Arvanites; Kelvin Lam; Steven Zimmerman; Sumin Jang; Stephen J Haggarty; David Kokel; Lee L Rubin; Randall T Peterson; Alexander F Schier
Journal:  Science       Date:  2010-01-15       Impact factor: 47.728

8.  A high-throughput screen for chemicals that increase the lifespan of Caenorhabditis elegans.

Authors:  Michael Petrascheck; Xiaolan Ye; Linda B Buck
Journal:  Ann N Y Acad Sci       Date:  2009-07       Impact factor: 5.691

9.  A whole-organism screen identifies new regulators of fat storage.

Authors:  George A Lemieux; Jason Liu; Nasima Mayer; Roland J Bainton; Kaveh Ashrafi; Zena Werb
Journal:  Nat Chem Biol       Date:  2011-03-13       Impact factor: 15.040

10.  Rapid behavior-based identification of neuroactive small molecules in the zebrafish.

Authors:  David Kokel; Jennifer Bryan; Christian Laggner; Rick White; Chung Yan J Cheung; Rita Mateus; David Healey; Sonia Kim; Andreas A Werdich; Stephen J Haggarty; Calum A Macrae; Brian Shoichet; Randall T Peterson
Journal:  Nat Chem Biol       Date:  2010-01-17       Impact factor: 15.040

  10 in total

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