| Literature DB >> 2142234 |
Abstract
The effect of toremifene on NK-cells isolated from the spleen of NZB/NZW mice was studied in comparison to tamoxifen and estradiol. Unlike estradiol but like tamoxifen, toremifene did not influence the activity of NK-cells. Low doses (0.1 and 10.0 mg/kg) of toremifene did not suppress, but a high dose of toremifene and tamoxifen (50 mg/kg for 6 weeks) suppressed the stimulating effect of human interferon alpha on the cells.Entities:
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Year: 1990 PMID： 2142234 DOI： 10.1016/0022-4731(90)90006-e
Source DB: PubMed Journal: J Steroid Biochem ISSN： 0022-4731 Impact factor: 4.292