Literature DB >> 21421011

Posttraining systemic administration of the histone deacetylase inhibitor sodium butyrate ameliorates aging-related memory decline in rats.

Gustavo K Reolon1, Natasha Maurmann, Aline Werenicz, Vanessa A Garcia, Nadja Schröder, Marcelo A Wood, Rafael Roesler.   

Abstract

Here we show that a systemic injection of the histone deacetylase inhibitor (HDACi) sodium butyrate (NaB) ameliorated an aging-associated deficit in object recognition memory in rats when the injection was given immediately, but not 6h after training. NaB had no effect in younger rats with normal memory retention. The results indicate that HDACis can ameliorate aging-related memory impairments by influencing the early consolidation phase of memory formation.
Copyright © 2011 Elsevier B.V. All rights reserved.

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Year:  2011        PMID： 21421011      PMCID： PMC3093300          DOI： 10.1016/j.bbr.2011.03.033

Source DB:  PubMed          Journal:  Behav Brain Res        ISSN： 0166-4328            Impact factor:   3.332


  24 in total

1.  Regulation of histone acetylation during memory formation in the hippocampus.

Authors:  Jonathan M Levenson; Kenneth J O'Riordan; Karen D Brown; Mimi A Trinh; David L Molfese; J David Sweatt
Journal:  J Biol Chem       Date:  2004-07-23       Impact factor: 5.157

2.  Neuroscience. Epigenetics and cognitive aging.

Authors:  J David Sweatt
Journal:  Science       Date:  2010-05-07       Impact factor: 47.728

3.  Reversal of age-related deficits in object recognition memory in rats with l-deprenyl.

Authors:  Maria Noêmia M de Lima; Daniela C Laranja; Fábio Caldana; Elke Bromberg; Rafael Roesler; Nadja Schröder
Journal:  Exp Gerontol       Date:  2005-04-02       Impact factor: 4.032

4.  HDAC inhibition modulates hippocampus-dependent long-term memory for object location in a CBP-dependent manner.

Authors:  Jakob Haettig; Daniel P Stefanko; Monica L Multani; Dario X Figueroa; Susan C McQuown; Marcelo A Wood
Journal:  Learn Mem       Date:  2011-01-11       Impact factor: 2.460

5.  Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease.

Authors:  Mark Kilgore; Courtney A Miller; Daniel M Fass; Krista M Hennig; Stephen J Haggarty; J David Sweatt; Gavin Rumbaugh
Journal:  Neuropsychopharmacology       Date:  2009-12-09       Impact factor: 7.853

6.  An epigenetic hypothesis of aging-related cognitive dysfunction.

Authors:  Marsha R Penner; Tania L Roth; Carol A Barnes; J David Sweatt
Journal:  Front Aging Neurosci       Date:  2010-03-12       Impact factor: 5.750

7.  Histone deactylase inhibition combined with behavioral therapy enhances learning and memory following traumatic brain injury.

Authors:  P K Dash; S A Orsi; A N Moore
Journal:  Neuroscience       Date:  2009-06-13       Impact factor: 3.590

8.  Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration.

Authors:  Juan M Alarcón; Gaël Malleret; Khalid Touzani; Svetlana Vronskaya; Shunsuke Ishii; Eric R Kandel; Angel Barco
Journal:  Neuron       Date:  2004-06-24       Impact factor: 17.173

9.  Histone deacetylase inhibitors improve learning consolidation in young and in KA-induced-neurodegeneration and SAMP-8-mutant mice.

Authors:  Angela Fontán-Lozano; Rocío Romero-Granados; Julieta Troncoso; Alejandro Múnera; José María Delgado-García; Angel M Carrión
Journal:  Mol Cell Neurosci       Date:  2008-06-25       Impact factor: 4.314

10.  Memantine reduces oxidative damage and enhances long-term recognition memory in aged rats.

Authors:  C Pietá Dias; M N Martins de Lima; J Presti-Torres; A Dornelles; V A Garcia; F Siciliani Scalco; M Rewsaat Guimarães; L Constantino; P Budni; Felipe Dal-Pizzol; N Schröder
Journal:  Neuroscience       Date:  2007-04-19       Impact factor: 3.590
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  31 in total

1.  Increasing histone acetylation in the hippocampus-infralimbic network enhances fear extinction.

Authors:  James M Stafford; Jonathan D Raybuck; Andrey E Ryabinin; K Matthew Lattal
Journal:  Biol Psychiatry       Date:  2012-01-29       Impact factor: 13.382

Review 2.  Improving healthspan via changes in gut microbiota and fermentation.

Authors:  Michael J Keenan; Maria L Marco; Donald K Ingram; Roy J Martin
Journal:  Age (Dordr)       Date:  2015-09-14

3.  Histone deacetylase and acetyltransferase inhibitors modulate behavioral responses to social stress.

Authors:  Katharine E McCann; Anna M Rosenhauer; Genna M F Jones; Alisa Norvelle; Dennis C Choi; Kim L Huhman
Journal:  Psychoneuroendocrinology       Date:  2016-10-26       Impact factor: 4.905

Review 4.  Histone acetylation: molecular mnemonics on the chromatin.

Authors:  Johannes Gräff; Li-Huei Tsai
Journal:  Nat Rev Neurosci       Date:  2013-01-17       Impact factor: 34.870

5.  TrkB blockade in the hippocampus after training or retrieval impairs memory: protection from consolidation impairment by histone deacetylase inhibition.

Authors:  Martina Blank; Fernanda S Petry; Martina Lichtenfels; Fernanda E Valiati; Arethuza S Dornelles; Rafael Roesler
Journal:  J Neural Transm (Vienna)       Date:  2015-10-01       Impact factor: 3.575

6.  Intraperitoneal administration of butyrate prevents the severity of acetic acid colitis in rats.

Authors:  Joshua J Malago; Catherine L Sangu
Journal:  J Zhejiang Univ Sci B       Date:  2015-03       Impact factor: 3.066

7.  Histone Deacetylase 2 Inhibition Attenuates Downregulation of Hippocampal Plasticity Gene Expression during Aging.

Authors:  Padmanabh Singh; M K Thakur
Journal:  Mol Neurobiol       Date:  2017-03-31       Impact factor: 5.590

8.  Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET.

Authors:  Sung Won Kim; Jacob M Hooker; Nicola Otto; Khaing Win; Lisa Muench; Colleen Shea; Pauline Carter; Payton King; Alicia E Reid; Nora D Volkow; Joanna S Fowler
Journal:  Nucl Med Biol       Date:  2013-07-29       Impact factor: 2.408

9.  HDAC inhibitor-dependent transcriptome and memory reinstatement in cognitive decline models.

Authors:  Eva Benito; Hendrik Urbanke; Binu Ramachandran; Jonas Barth; Rashi Halder; Ankit Awasthi; Gaurav Jain; Vincenzo Capece; Susanne Burkhardt; Magdalena Navarro-Sala; Sankari Nagarajan; Anna-Lena Schütz; Steven A Johnsen; Stefan Bonn; Reinhardt Lührmann; Camin Dean; André Fischer
Journal:  J Clin Invest       Date:  2015-08-17       Impact factor: 14.808

10.  Exercise induces age-dependent changes on epigenetic parameters in rat hippocampus: a preliminary study.

Authors:  Viviane Rostirola Elsner; Gisele Agustini Lovatel; Felipe Moysés; Karine Bertoldi; Christiano Spindler; Laura Reck Cechinel; Alysson Renato Muotri; Ionara Rodrigues Siqueira
Journal:  Exp Gerontol       Date:  2012-11-30       Impact factor: 4.032
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