| Literature DB >> 21419337 |
Michael L Gleghorn1, Lynne E Maquat.
Abstract
In this issue of Molecular Cell, Chakrabarti et al. (2011) structurally reveal how UPF1, an RNA helicase that plays a central role in nonsense-mediated mRNA decay, is conformationally converted from a largely inactive state to an active state upon UPF2 binding.Entities:
Year: 2011 PMID： 21419337 DOI： 10.1016/j.molcel.2011.03.001
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970