Literature DB >> 21415854

A fresh look at cancer metabolism in a historical setting.

Almut Schulze1.   

Abstract

The Institute for Research in Biomedicine (IRB) Barcelona meeting on Cancer Metabolism took place in November 2010. It was organized with the support of the Banco Bilbao Vizcaya Argentaria Foundation and offered an outstanding line-up of acclaimed speakers within an intimate setting that allowed plenty of opportunity for informal interactions.

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Year:  2011        PMID： 21415854      PMCID： PMC3077258          DOI： 10.1038/embor.2011.44

Source DB:  PubMed          Journal:  EMBO Rep        ISSN： 1469-221X            Impact factor:   8.807


  11 in total

1.  Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes.

Authors:  Sergio L Colombo; Miriam Palacios-Callender; Nanci Frakich; Joel De Leon; Christoph A Schmitt; Leanne Boorn; Nicola Davis; Salvador Moncada
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-04       Impact factor: 11.205

2.  Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase.

Authors:  Jamel Mankouri; Philip R Tedbury; Sarah Gretton; Mair E Hughes; Stephen D C Griffin; Mark L Dallas; Kevin A Green; D Grahame Hardie; Chris Peers; Mark Harris
Journal:  Proc Natl Acad Sci U S A       Date:  2010-06-07       Impact factor: 11.205

3.  The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.

Authors:  Angel Herrero-Mendez; Angeles Almeida; Emilio Fernández; Carolina Maestre; Salvador Moncada; Juan P Bolaños
Journal:  Nat Cell Biol       Date:  2009-05-17       Impact factor: 28.824

4.  Activation of a metabolic gene regulatory network downstream of mTOR complex 1.

Authors:  Katrin Düvel; Jessica L Yecies; Suchithra Menon; Pichai Raman; Alex I Lipovsky; Amanda L Souza; Ellen Triantafellow; Qicheng Ma; Regina Gorski; Stephen Cleaver; Matthew G Vander Heiden; Jeffrey P MacKeigan; Peter M Finan; Clary B Clish; Leon O Murphy; Brendan D Manning
Journal:  Mol Cell       Date:  2010-07-30       Impact factor: 17.970

5.  AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.

Authors:  Joungmok Kim; Mondira Kundu; Benoit Viollet; Kun-Liang Guan
Journal:  Nat Cell Biol       Date:  2011-01-23       Impact factor: 28.824

6.  Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

Authors:  Lenny Dang; David W White; Stefan Gross; Bryson D Bennett; Mark A Bittinger; Edward M Driggers; Valeria R Fantin; Hyun Gyung Jang; Shengfang Jin; Marie C Keenan; Kevin M Marks; Robert M Prins; Patrick S Ward; Katharine E Yen; Linda M Liau; Joshua D Rabinowitz; Lewis C Cantley; Craig B Thompson; Matthew G Vander Heiden; Shinsan M Su
Journal:  Nature       Date:  2009-12-10       Impact factor: 49.962

7.  Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH.

Authors:  Johanna Chiche; Karine Ilc; Julie Laferrière; Eric Trottier; Frédéric Dayan; Nathalie M Mazure; M Christiane Brahimi-Horn; Jacques Pouysségur
Journal:  Cancer Res       Date:  2009-01-01       Impact factor: 12.701

8.  O2 regulates stem cells through Wnt/β-catenin signalling.

Authors:  Jolly Mazumdar; W Timothy O'Brien; Randall S Johnson; Joseph C LaManna; Juan C Chavez; Peter S Klein; M Celeste Simon
Journal:  Nat Cell Biol       Date:  2010-09-19       Impact factor: 28.824

9.  The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.

Authors:  Patrick S Ward; Jay Patel; David R Wise; Omar Abdel-Wahab; Bryson D Bennett; Hilary A Coller; Justin R Cross; Valeria R Fantin; Cyrus V Hedvat; Alexander E Perl; Joshua D Rabinowitz; Martin Carroll; Shinsan M Su; Kim A Sharp; Ross L Levine; Craig B Thompson
Journal:  Cancer Cell       Date:  2010-02-18       Impact factor: 38.585

10.  SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth.

Authors:  Thomas Porstmann; Claudio R Santos; Beatrice Griffiths; Megan Cully; Mary Wu; Sally Leevers; John R Griffiths; Yuen-Li Chung; Almut Schulze
Journal:  Cell Metab       Date:  2008-09       Impact factor: 27.287
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