BACKGROUND: Many ambulatory children with spina bifida (SB) decline in their walking despite stable or even improved motor function. OBJECTIVE: The authors evaluated the effects of a home-based treadmill training program on both ambulatory function and aerobic fitness. METHODS: This randomized clinical trial of 34 ambulatory children with SB allocated 18 tosupervised treadmill training for 12 weeks at home and 14 to usual care. Patients in home training exercised twice a week at an intensity of 66% of HR(peak) (peak heart rate) and gradually progressed from 70% to 140% of their individual walking speed. Main outcome measures were obtained at baseline, after intervention, and 3 months postintervention. Ambulation was measured using the 6-minute walk test (6MWT), during which gross energy consumption (ECS(gross)) and energy cost were calculated. Maximal exercise capacity was measured using an incremental treadmill test. Both VO(2peak) and speed(peak) were recorded as outcome parameters. RESULTS: After training, significant changes were seen between the groups for 6MWT (P = .002; d = 1.08), speed(peak) (P = .001; d = 1.14), VO(2peak) (P = .034; d = 0.78), and ECS(gross) (P = .004; d = 1.01). Long-term effects were recorded for 6MWT (P = .003; η = 0.34), speed(peak) (P = .003; η = 0.35), and ECS(gross) (P = .014; η = 0.29) but not for VO(2peak). CONCLUSION: A home-based, progressive treadmill training program for ambulatory children with SB has a large long-term effect on ambulation, with a moderate short-term effect on VO(2peak).
RCT Entities:
BACKGROUND: Many ambulatory children with spina bifida (SB) decline in their walking despite stable or even improved motor function. OBJECTIVE: The authors evaluated the effects of a home-based treadmill training program on both ambulatory function and aerobic fitness. METHODS: This randomized clinical trial of 34 ambulatory children with SB allocated 18 to supervised treadmill training for 12 weeks at home and 14 to usual care. Patients in home training exercised twice a week at an intensity of 66% of HR(peak) (peak heart rate) and gradually progressed from 70% to 140% of their individual walking speed. Main outcome measures were obtained at baseline, after intervention, and 3 months postintervention. Ambulation was measured using the 6-minute walk test (6MWT), during which gross energy consumption (ECS(gross)) and energy cost were calculated. Maximal exercise capacity was measured using an incremental treadmill test. Both VO(2peak) and speed(peak) were recorded as outcome parameters. RESULTS: After training, significant changes were seen between the groups for 6MWT (P = .002; d = 1.08), speed(peak) (P = .001; d = 1.14), VO(2peak) (P = .034; d = 0.78), and ECS(gross) (P = .004; d = 1.01). Long-term effects were recorded for 6MWT (P = .003; η = 0.34), speed(peak) (P = .003; η = 0.35), and ECS(gross) (P = .014; η = 0.29) but not for VO(2peak). CONCLUSION: A home-based, progressive treadmill training program for ambulatory children with SB has a large long-term effect on ambulation, with a moderate short-term effect on VO(2peak).
Authors: Manon A T Bloemen; Olaf Verschuren; Claudia van Mechelen; Hanneke E Borst; Arina J de Leeuw; Marsha van der Hoef; Janke F de Groot Journal: BMC Neurol Date: 2015-02-10 Impact factor: 2.474
Authors: Thomas D O'Brien; Jane Noyes; Llinos Haf Spencer; Hans-Peter Kubis; Richard P Hastings; Rhiannon Whitaker Journal: BMJ Open Sport Exerc Med Date: 2016-11-15
Authors: Mark Jennings; Aoife Guilfoyle; James Green; Yvonne Cleary; Rosemary Joan Gowran Journal: Int J Environ Res Public Health Date: 2020-11-10 Impact factor: 3.390
Authors: Maremka Zwinkels; Olaf Verschuren; Kristel Lankhorst; Karin van der Ende-Kastelijn; Janke de Groot; Frank Backx; Anne Visser-Meily; Tim Takken Journal: BMC Sports Sci Med Rehabil Date: 2015-10-06