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Literature DB >> 21412230

A fresh look at the mechanism of isoniazid-induced hepatotoxicity.

I G Metushi¹, P Cai, X Zhu, T Nakagawa, J P Uetrecht.

Abstract

Entities: Chemical Disease

Mesh：

Substances：
Isoniazid

Year: 2011 PMID： 21412230 DOI： 10.1038/clpt.2010.355

Source DB: PubMed Journal: Clin Pharmacol Ther ISSN： 0009-9236 Impact factor: 6.875

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42 in total

Review 1. Arylamine N-acetyltransferases: a structural perspective.

Authors: Xiaotong Zhou; Zhiguo Ma; Dong Dong; Baojian Wu
Journal: Br J Pharmacol Date: 2013-06 Impact factor: 8.739

2. A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis.

Authors: Rachel J Church; Hong Wu; Merrie Mosedale; Susan J Sumner; Wimal Pathmasiri; Catherine L Kurtz; Mathew T Pletcher; John S Eaddy; Karamjeet Pandher; Monica Singer; Ameesha Batheja; Paul B Watkins; Karissa Adkins; Alison H Harrill
Journal: Toxicol Sci Date: 2014-05-20 Impact factor: 4.849

3. Induction of protective autophagy against apoptosis in HepG2 cells by isoniazid independent of the p38 signaling pathway.

Authors: Tian-Guang Zhang; Yi-Mei Wang; Jun Zhao; Ming-Yu Xia; Shuang-Qing Peng; Takashi Ikejima
Journal: Toxicol Res (Camb) Date: 2016-04-04 Impact factor: 3.524

4. Hepatoprotective activity of viscosine is mediated by attenuation of hepatic macrophages and iNOS expression in CCl₄-intoxicated rats.

Authors: Hamid Ali; Nurul Kabir; Muhammad Raza Shah; Akhtar Muhammad; Safdar Ali; Shahab Mehmood; Amjad Ali; Abid Ali; Azra Jahan
Journal: Toxicol Res (Camb) Date: 2016-09-13 Impact factor: 3.524

5. Diallyl trisulfide protects the liver against hepatotoxicity induced by isoniazid and rifampin in mice by reducing oxidative stress and activating Kupffer cells.

Authors: Yilin Yang; Lulu Jiang; Shuo Wang; Tao Zeng; Keqin Xie
Journal: Toxicol Res (Camb) Date: 2016-04-01 Impact factor: 3.524

6. Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment.

Authors: Hozeifa Mohamed Hassan; Hongli Guo; Bashir Alsiddig Yousef; Mounia Guerram; Aida Mejda Hamdi; Luyong Zhang; Zhenzhou Jiang
Journal: Antimicrob Agents Chemother Date: 2016-08-22 Impact factor: 5.191

A fresh look at the mechanism of isoniazid-induced hepatotoxicity.

Review 1. Arylamine N-acetyltransferases: a structural perspective.

2. A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis.

3. Induction of protective autophagy against apoptosis in HepG2 cells by isoniazid independent of the p38 signaling pathway.

4. Hepatoprotective activity of viscosine is mediated by attenuation of hepatic macrophages and iNOS expression in CCl₄-intoxicated rats.

5. Diallyl trisulfide protects the liver against hepatotoxicity induced by isoniazid and rifampin in mice by reducing oxidative stress and activating Kupffer cells.

6. Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment.

Review 7. Hepatotoxicity Related to Anti-tuberculosis Drugs: Mechanisms and Management.

8. Quantification of Hydrazine in Human Urine by HPLC-MS-MS.

9. Relationship between characteristics of medications and drug-induced liver disease phenotype and outcome.

10. Detection of anti-isoniazid and anti-cytochrome P450 antibodies in patients with isoniazid-induced liver failure.