Literature DB >> 21411536

The mouse cytomegalovirus glycoprotein m155 inhibits CD40 expression and restricts CD4 T cell responses.

Andrea I Loewendorf1, Lars Steinbrueck, Christoph Peter, Andreas Busche, Chris A Benedict, Penelope C Kay-Jackson.   

Abstract

Cytomegaloviruses (CMV) utilize a variety of immunomodulatory strategies to facilitate the establishment of lifelong persistence in their infected hosts. We show that the mouse CMV (MCMV) m155 open reading frame (ORF) is required for the posttranscriptional inhibition of CD40 expression in infected antigen-presenting cells. Consistent with the known importance of CD40-mediated costimulation of T cells, a m155-deficient virus induces enhanced MCMV epitope-specific CD4 T cell responses.

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Year:  2011        PMID： 21411536      PMCID： PMC3126186          DOI： 10.1128/JVI.02178-10

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  49 in total

1.  Structural elucidation of the m157 mouse cytomegalovirus ligand for Ly49 natural killer cell receptors.

Authors:  Erin J Adams; Z Sean Juo; Rayna Takaki Venook; Martin J Boulanger; Hisashi Arase; Lewis L Lanier; K Christopher Garcia
Journal:  Proc Natl Acad Sci U S A       Date:  2007-05-30       Impact factor: 11.205

2.  Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules.

Authors:  Z Shen; G Reznikoff; G Dranoff; K L Rock
Journal:  J Immunol       Date:  1997-03-15       Impact factor: 5.422

3.  Mechanisms of immunosuppression in cytomegalovirus mononucleosis. II. Virus-monocyte interactions.

Authors:  W P Carney; M S Hirsch
Journal:  J Infect Dis       Date:  1981-07       Impact factor: 5.226

4.  A mouse cytomegalovirus glycoprotein retains MHC class I complexes in the ERGIC/cis-Golgi compartments.

Authors:  H Ziegler; R Thale; P Lucin; W Muranyi; T Flohr; H Hengel; H Farrell; W Rawlinson; U H Koszinowski
Journal:  Immunity       Date:  1997-01       Impact factor: 31.745

5.  Transient subversion of CD40 ligand function diminishes immune responses to adenovirus vectors in mouse liver and lung tissues.

Authors:  Y Yang; Q Su; I S Grewal; R Schilz; R A Flavell; J M Wilson
Journal:  J Virol       Date:  1996-09       Impact factor: 5.103

6.  Analysis of the complete DNA sequence of murine cytomegalovirus.

Authors:  W D Rawlinson; H E Farrell; B G Barrell
Journal:  J Virol       Date:  1996-12       Impact factor: 5.103

7.  Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway.

Authors:  Chris A Benedict; Andrea Loewendorf; Zacarias Garcia; Bruce R Blazar; Edith M Janssen
Journal:  J Immunol       Date:  2008-04-01       Impact factor: 5.422

8.  Cellular expression and crystal structure of the murine cytomegalovirus major histocompatibility complex class I-like glycoprotein, m153.

Authors:  Janet Mans; Kannan Natarajan; Andrea Balbo; Peter Schuck; Daniel Eikel; Sonja Hess; Howard Robinson; Hrvoje Simic; Stipan Jonjic; Caroline T Tiemessen; David H Margulies
Journal:  J Biol Chem       Date:  2007-09-26       Impact factor: 5.157

9.  Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand.

Authors:  I S Grewal; J Xu; R A Flavell
Journal:  Nature       Date:  1995-12-07       Impact factor: 49.962

10.  The cytomegalovirus m155 gene product subverts natural killer cell antiviral protection by disruption of H60-NKG2D interactions.

Authors:  Melissa B Lodoen; Gerardo Abenes; Sean Umamoto; Jeffrey P Houchins; Fenyong Liu; Lewis L Lanier
Journal:  J Exp Med       Date:  2004-10-11       Impact factor: 14.307
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  10 in total

1.  Murine cytomegalovirus downregulates interleukin-17 in mice with retrovirus-induced immunosuppression that are susceptible to experimental cytomegalovirus retinitis.

Authors:  Emily L Blalock; Hsin Chien; Richard D Dix
Journal:  Cytokine       Date:  2013-02-14       Impact factor: 3.861

Review 2.  MCMV avoidance of recognition and control by NK cells.

Authors:  Ilija Brizić; Tihana Lenac Roviš; Astrid Krmpotić; Stipan Jonjić
Journal:  Semin Immunopathol       Date:  2014-08-21       Impact factor: 9.623

3.  Human herpesvirus 7 U21 tetramerizes to associate with class I major histocompatibility complex molecules.

Authors:  Nathan A May; Qiuhong Wang; Andrea Balbo; Sheryl L Konrad; Rico Buchli; William H Hildebrand; Peter Schuck; Amy W Hudson
Journal:  J Virol       Date:  2014-01-03       Impact factor: 5.103

4.  Antiviral T cell response triggers cytomegalovirus hepatitis in mice.

Authors:  Devon Livingston-Rosanoff; Lisa P Daley-Bauer; AnaPatricia Garcia; A Louise McCormick; Jing Huang; Edward S Mocarski
Journal:  J Virol       Date:  2012-09-19       Impact factor: 5.103

Review 5.  Cytomegalovirus: Shape-Shifting the Immune System.

Authors:  Gaëlle Picarda; Chris A Benedict
Journal:  J Immunol       Date:  2018-06-15       Impact factor: 5.422

Review 6.  Cytomegalovirus immune evasion by perturbation of endosomal trafficking.

Authors:  Pero Lučin; Hana Mahmutefendić; Gordana Blagojević Zagorac; Maja Ilić Tomaš
Journal:  Cell Mol Immunol       Date:  2014-09-29       Impact factor: 11.530

7.  Manipulation of NKG2D ligands by cytomegaloviruses: impact on innate and adaptive immune response.

Authors:  Irena Slavuljica; Astrid Krmpotić; Stipan Jonjić
Journal:  Front Immunol       Date:  2011-12-28       Impact factor: 7.561

8.  Cytomegalovirus m154 hinders CD48 cell-surface expression and promotes viral escape from host natural killer cell control.

Authors:  Angela Zarama; Natàlia Pérez-Carmona; Domènec Farré; Adriana Tomic; Eva Maria Borst; Martin Messerle; Stipan Jonjic; Pablo Engel; Ana Angulo
Journal:  PLoS Pathog       Date:  2014-03-13       Impact factor: 6.823

Review 9.  Deciphering the role of DC subsets in MCMV infection to better understand immune protection against viral infections.

Authors:  Yannick O Alexandre; Clément D Cocita; Sonia Ghilas; Marc Dalod
Journal:  Front Microbiol       Date:  2014-07-29       Impact factor: 5.640

Review 10.  Host-Adapted Gene Families Involved in Murine Cytomegalovirus Immune Evasion.

Authors:  Sara Becker; Annette Fink; Jürgen Podlech; Matthias J Reddehase; Niels A Lemmermann
Journal:  Viruses       Date:  2022-01-11       Impact factor: 5.048
  10 in total

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