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Literature DB >> 2141094

Metabolic dynamics in the human red cell. Part IV--Data prediction and some model computations.

Abstract

The biochemical information on the basic cellular determinants of the human red cell has been compiled into a comprehensive model of the red cell metabolic machinery. This model gives a consistent interpretation--both qualitative and quantitative--of the experimental findings. The predicted steady states and the dynamic states of the model are compared with the experimental findings, and the utility of this model is demonstrated.

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Year: 1990 PMID： 2141094 DOI： 10.1016/s0022-5193(05)80013-x

Source DB: PubMed Journal: J Theor Biol ISSN： 0022-5193 Impact factor: 2.691

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Cited

12 in total

1. Description and analysis of metabolic connectivity and dynamics in the human red blood cell.

Authors: Kenneth J Kauffman; John David Pajerowski; Neema Jamshidi; Bernhard O Palsson; Jeremy S Edwards
Journal: Biophys J Date: 2002-08 Impact factor: 4.033

2. Mass action stoichiometric simulation models: incorporating kinetics and regulation into stoichiometric models.

Authors: Neema Jamshidi; Bernhard Ø Palsson
Journal: Biophys J Date: 2010-01-20 Impact factor: 4.033

3. In silico model-driven assessment of the effects of single nucleotide polymorphisms (SNPs) on human red blood cell metabolism.

Authors: Neema Jamshidi; Sharon J Wiback; Bernhard Ø Palsson B
Journal: Genome Res Date: 2002-11 Impact factor: 9.043

Review 4. Computing the functional proteome: recent progress and future prospects for genome-scale models.

Authors: Edward J O'Brien; Bernhard O Palsson
Journal: Curr Opin Biotechnol Date: 2015-01-08 Impact factor: 9.740

5. k-Cone analysis: determining all candidate values for kinetic parameters on a network scale.

Authors: Iman Famili; Radhakrishnan Mahadevan; Bernhard O Palsson
Journal: Biophys J Date: 2004-12-30 Impact factor: 4.033

6. Changes in Adenylate Nucleotides Concentration and Na, K-ATPase Activities in Erythrocytes of Horses in Function of Breed and Sex.

Authors: Maria Suska; Ewa Skotnicka
Journal: Vet Med Int Date: 2009-11-11

Metabolic dynamics in the human red cell. Part IV--Data prediction and some model computations.

1. Description and analysis of metabolic connectivity and dynamics in the human red blood cell.

2. Mass action stoichiometric simulation models: incorporating kinetics and regulation into stoichiometric models.

3. In silico model-driven assessment of the effects of single nucleotide polymorphisms (SNPs) on human red blood cell metabolism.

Review 4. Computing the functional proteome: recent progress and future prospects for genome-scale models.

5. k-Cone analysis: determining all candidate values for kinetic parameters on a network scale.

6. Changes in Adenylate Nucleotides Concentration and Na, K-ATPase Activities in Erythrocytes of Horses in Function of Breed and Sex.

7. Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network.

8. Dynamic simulation of red blood cell metabolism and its application to the analysis of a pathological condition.

9. Multi-timescale modeling of activity-dependent metabolic coupling in the neuron-glia-vasculature ensemble.

Review 10. Systems biology as an emerging paradigm in transfusion medicine.