| Literature DB >> 21410833 |
Glauco Baiocchi1, Carlos Chaves Faloppa, Cynthia Aparecida Bueno de Toledo Osório, Lillian Yuri Kumagai, Elza Mieko Fukazawa, Isabela Werneck Cunha.
Abstract
Embryonal rhabdomyosarcoma (RMS) of the female genital tract usually occurs in the vagina during childhood. The uterine cervix as a primary site is rare, but is more frequent until the second decade of life. It usually has a good prognosis and the treatment is based on multidrug chemotherapy, radiotherapy and surgery. RMS accounts for <5% of all adult soft tissue sarcomas. Previous reports that included all primary sites showed a poorer five-year disease specific survival for adults with RMS when compared to the pediatric population. This difference has been attributed to a higher proportion of adverse prognostic clinical and pathological factors, and to inadequate treatment given to adults with RMS. A total of 115 patients with cervical embryonal RMS have previously been described; however, only 10 cases were reported in women older than 40 years. We present a 47-year-old woman treated with radical hysterectomy followed by adjuvant chemotherapy and review the current literature.Entities:
Mesh:
Year: 2011 PMID: 21410833 DOI: 10.1111/j.1447-0756.2010.01449.x
Source DB: PubMed Journal: J Obstet Gynaecol Res ISSN: 1341-8076 Impact factor: 1.730