Literature DB >> 21409892

Vaginoplasty by using amnion graft in patients of vaginal agenesis associated with Mayor-Rokitansky-Kuster-Hauser syndrome.

Iram Sarwar1, Ruqqia Sultana, Rahat Un Nisa, Iftikhar Qayyum.   

Abstract

BACKGROUND: Vaginal agenesis is congenital anomaly of the female genital tract and may occur as isolated developmental defect or as part of a complex of anomalies. The aim of this study was to determine the effectiveness of vaginoplasty by using amnion as graft in the creation of neovagina for patients with Mayor-Rokitansky-Kuster-Hauser Syndrome.
METHODS: this is a retrospective study of 28 cases of vaginal agenesis associated with Mayor-Rokitansky-Kuster-Hauser Syndrome, over the period of 20 years, in which vaginoplasty was done by modified McIndoe procedure by using amnion as graft.
RESULTS: vaginoplasty using amnion graft was successfully performed in all except one case in which rectum got opened and procedure was abandoned after the repair of rectum. The functional results were quite satisfactory. Except one case none had any significant peri-operative complication. Post surgical results were acceptable to the patients sexually and aesthetically.
CONCLUSION: Although new techniques of vaginoplasty have evolved over the years using laparoscopic approach and by use of different materials as graft, vaginoplasty with amnion graft is still a safe and effective procedure to treat patients of vaginal agenesis. The technique is simple and safe and provides a satisfactory and functional vagina in majority of the patients.

Entities:  

Mesh:

Year:  2010        PMID: 21409892

Source DB:  PubMed          Journal:  J Ayub Med Coll Abbottabad        ISSN: 1025-9589


  5 in total

1.  Amniotic membrane scaffolds enable the development of tissue-engineered urothelium with molecular and ultrastructural properties comparable to that of native urothelium.

Authors:  Urška Dragin Jerman; Peter Veranič; Mateja Erdani Kreft
Journal:  Tissue Eng Part C Methods       Date:  2013-10-12       Impact factor: 3.056

Review 2.  Dilation and surgical management in vaginal agenesis: a systematic review.

Authors:  Sarah K McQuillan; Sonia R Grover
Journal:  Int Urogynecol J       Date:  2013-10-10       Impact factor: 2.894

Review 3.  Vaginoplasty with an Autologous Buccal Mucosa Fenestrated Graft in Two Patients with Vaginal Agenesis: A Multidisciplinary Approach and Literature Review.

Authors:  Jessica L Chan; Pamela J Levin; Brian P Ford; David C Stanton; Samantha M Pfeifer
Journal:  J Minim Invasive Gynecol       Date:  2017-02-15       Impact factor: 4.137

4.  Prospective randomized comparison of laparoscopic peritoneal vaginoplasty with laparoscopic sigmoid vaginoplasty for treating congenital vaginal agenesis.

Authors:  Lili Cao; Yanzhou Wang; Yudi Li; Huicheng Xu
Journal:  Int Urogynecol J       Date:  2012-12-01       Impact factor: 2.894

Review 5.  Amniotic therapeutic biomaterials in urology: current and future applications.

Authors:  Siam Oottamasathien; James M Hotaling; James R Craig; Jeremy B Myers; William O Brant
Journal:  Transl Androl Urol       Date:  2017-10
  5 in total

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