Literature DB >> 21409317

In vivo imaging neurotransmitter function. The rat 6-hydroxydopamine model and its relevance for human Parkinson's disease.

S Nikolaus1, R Larisch, H Vosberg, M Beu, H Hautzel, A Wirrwar, H-W Mueller, C Antke.   

Abstract

This article gives an overview of those small animal imaging studies which have been conducted on neurotransmitter function in the rat 6-hydoxydopamine (6-OHDA) model of Parkinson's disease, and discusses findings with respect to the outcome of clinical studies on Parkinsonian patients.

Entities:  

Mesh:

Substances:

Year:  2011        PMID: 21409317     DOI: 10.3413/Nukmed-0371-10-12

Source DB:  PubMed          Journal:  Nuklearmedizin        ISSN: 0029-5566            Impact factor:   1.379


  1 in total

1.  High correlation between in vivo [123I]β-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA in rats.

Authors:  Susanne Bäck; Mari Raki; Raimo K Tuominen; Atso Raasmaja; Kim Bergström; Pekka T Männistö
Journal:  EJNMMI Res       Date:  2013-06-10       Impact factor: 3.138

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.