Literature DB >> 2140848

Plasma tryptophan to large neutral amino acid ratios in depressed and normal subjects.

M J Russ1, S H Ackerman, M Banay-Schwartz, R D Shindledecker, G P Smith.   

Abstract

The ratios of total and free plasma tryptophan to the sum of five large neutral amino acids (LNAAs) were found to be significantly lower in a group of 16 depressed inpatients compared to nine normal subjects after oral loading with L-tryptophan. The group differences in these ratios were significant before, and 2 weeks after starting treatment with a tricyclic antidepressant. Plasma tryptophan ratios and severity of depression were not significantly correlated.

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Year:  1990        PMID： 2140848     DOI： 10.1016/0165-0327(90)90003-q

Source DB:  PubMed          Journal:  J Affect Disord        ISSN： 0165-0327            Impact factor:   4.839


  4 in total

1.  Serotonin-immune interactions in major depression: lower serum tryptophan as a marker of an immune-inflammatory response.

Authors:  M Maes; R Verkerk; E Vandoolaeghe; F Van Hunsel; H Neels; A Wauters; P Demedts; S Scharpé
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  1997       Impact factor: 5.270

2.  Specificity of the acute tryptophan and tyrosine plus phenylalanine depletion and loading tests I. Review of biochemical aspects and poor specificity of current amino Acid formulations.

Authors:  Abdulla A-B Badawy; Donald M Dougherty; Dawn M Richard
Journal:  Int J Tryptophan Res       Date:  2010-01-01

3.  Individual day-to-day variations in plasma amino acid levels in healthy persons.

Authors:  J Demling; K Langer; M Wörthmüller; V Yusufu
Journal:  Amino Acids       Date:  1993-06       Impact factor: 3.520

4.  Brain Versus Blood: A Systematic Review on the Concordance Between Peripheral and Central Kynurenine Pathway Measures in Psychiatric Disorders.

Authors:  Katrien Skorobogatov; Livia De Picker; Robert Verkerk; Violette Coppens; Marion Leboyer; Norbert Müller; Manuel Morrens
Journal:  Front Immunol       Date:  2021-09-23       Impact factor: 7.561
  4 in total

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