PURPOSE: We examined the effect of β-alanine supplementation plus sodium bicarbonate on high-intensity cycling capacity. METHODS:Twenty males (age = 25 ± 5 yr, height = 1.79 ± 0.06 m, body mass = 80.0 ± 10.3 kg) were assigned to either a placebo (P) or a β-alanine (BA; 6.4 g·d(-1) for 4 wk) group based on power max, completing four cycling capacity tests at 110% of power max (CCT110%) to determine time to exhaustion (TTE) and total work done. A CCT(110%) was performed twice (habituation and baseline) before supplementation (with maltodextrin [MD]) and twice after supplementation (with MD and with sodium bicarbonate [SB]), using a crossover design with 2 d of rest between trials, creating four study conditions (PMD, PSB, BAMD, and BASB). Blood pH, Lactate, bicarbonate and base excess were determined at baseline, before exercise, immediately after exercise, and 5 min after exercise. Data were analyzed using repeated-measures ANOVA. RESULTS:TTE was increased in all conditions after supplementation (+1.6% PMD, +6.5% PSB, +12.1% BAMD, and +16.2% BASB). Both BAMD and BASB resulted in significantly improved TTE compared with that before supplementation (P ≤ 0.01). Although further increases in TTE (4.1%) were shown in BASB compared with BAMD, these differences were not significant (P = 0.74). Differences in total work done were similar to those of TTE. Blood bicarbonate concentrations were significantly (P ≤ 0.001) elevated before exercise in PSB and BASB but not in PMD or BAMD. Blood lactate concentrations were significantly elevated after exercise, remaining elevated after 5 min of recovery (P ≤ 0.001) and were highest in PSB and BASB. CONCLUSIONS: Results show that BA improved high-intensity cycling capacity. However, despite a 6-s (∼4%) increase in TTE with the addition of SB, this did not reach statistical significance, but magnitude-based inferences suggested a ∼70% probability of a meaningful positive difference.
RCT Entities:
PURPOSE: We examined the effect of β-alanine supplementation plus sodium bicarbonate on high-intensity cycling capacity. METHODS: Twenty males (age = 25 ± 5 yr, height = 1.79 ± 0.06 m, body mass = 80.0 ± 10.3 kg) were assigned to either a placebo (P) or a β-alanine (BA; 6.4 g·d(-1) for 4 wk) group based on power max, completing four cycling capacity tests at 110% of power max (CCT110%) to determine time to exhaustion (TTE) and total work done. A CCT(110%) was performed twice (habituation and baseline) before supplementation (with maltodextrin [MD]) and twice after supplementation (with MD and with sodium bicarbonate [SB]), using a crossover design with 2 d of rest between trials, creating four study conditions (PMD, PSB, BAMD, and BASB). Blood pH, Lactate, bicarbonate and base excess were determined at baseline, before exercise, immediately after exercise, and 5 min after exercise. Data were analyzed using repeated-measures ANOVA. RESULTS: TTE was increased in all conditions after supplementation (+1.6% PMD, +6.5% PSB, +12.1% BAMD, and +16.2% BASB). Both BAMD and BASB resulted in significantly improved TTE compared with that before supplementation (P ≤ 0.01). Although further increases in TTE (4.1%) were shown in BASB compared with BAMD, these differences were not significant (P = 0.74). Differences in total work done were similar to those of TTE. Blood bicarbonate concentrations were significantly (P ≤ 0.001) elevated before exercise in PSB and BASB but not in PMD or BAMD. Blood lactate concentrations were significantly elevated after exercise, remaining elevated after 5 min of recovery (P ≤ 0.001) and were highest in PSB and BASB. CONCLUSIONS: Results show that BA improved high-intensity cycling capacity. However, despite a 6-s (∼4%) increase in TTE with the addition of SB, this did not reach statistical significance, but magnitude-based inferences suggested a ∼70% probability of a meaningful positive difference.
Authors: Luana Farias de Oliveira; Eimear Dolan; Paul A Swinton; Krzysztof Durkalec-Michalski; Guilherme G Artioli; Lars R McNaughton; Bryan Saunders Journal: Sports Med Date: 2021-10-23 Impact factor: 11.136
Authors: Micah Gross; Chris Boesch; Christine S Bolliger; Barbara Norman; Thomas Gustafsson; Hans Hoppeler; Michael Vogt Journal: Eur J Appl Physiol Date: 2013-11-09 Impact factor: 3.078
Authors: Serena del Favero; Hamilton Roschel; Marina Y Solis; Ana P Hayashi; Guilherme G Artioli; Maria Concepción Otaduy; Fabiana B Benatti; Roger C Harris; John A Wise; Cláudia C Leite; Rosa M Pereira; Ana L de Sá-Pinto; Antonio Herbert Lancha-Junior; Bruno Gualano Journal: Amino Acids Date: 2011-12-06 Impact factor: 3.520
Authors: Bill Campbell; Colin Wilborn; Lem Taylor; Mike Greenwood; Stephen Schmitz; Rick Collins; Jose Antonio; Paul La Bounty; Mike T Nelson; Tim N Ziegenfuss; Hector L Lopez; Jay R Hoffman; Jeffrey R Stout; Doug S Kalman; Richard B Kreider Journal: J Int Soc Sports Nutr Date: 2013-01-03 Impact factor: 5.150