OBJECTIVE: The aim of this study was to assess the balance and vestibular systems in healthy workers exposed to low concentrations of organic solvent mixtures. METHODS: The study groups comprised 60 workers exposed to mixture of organic solvents and 110 reference workers. All subjects performed static posturography and electronystagmography (ENG). RESULTS: In posturography, abnormal reaction time was more frequent and statistically longer in solvent-exposed group. Also, worse results of movement coordination parameters were observed in this group. The ENG square waves and abnormal optokinetic results were more common in exposed group. Mean caloric response was shorter in the exposed group. Negative relationship was found between time of caloric response and cumulative toluene concentration. CONCLUSIONS: Balance abnormalities in solvent-exposed workers indicated subclinical damage, mainly of central part of vestibular system and body-movement coordination. It would not be reasonable to exclude the vestibular hyporeactivity.
OBJECTIVE: The aim of this study was to assess the balance and vestibular systems in healthy workers exposed to low concentrations of organic solvent mixtures. METHODS: The study groups comprised 60 workers exposed to mixture of organic solvents and 110 reference workers. All subjects performed static posturography and electronystagmography (ENG). RESULTS: In posturography, abnormal reaction time was more frequent and statistically longer in solvent-exposed group. Also, worse results of movement coordination parameters were observed in this group. The ENG square waves and abnormal optokinetic results were more common in exposed group. Mean caloric response was shorter in the exposed group. Negative relationship was found between time of caloric response and cumulative toluene concentration. CONCLUSIONS: Balance abnormalities in solvent-exposed workers indicated subclinical damage, mainly of central part of vestibular system and body-movement coordination. It would not be reasonable to exclude the vestibular hyporeactivity.
Authors: Ha T Nguyen; Stephen B Kritchevsky; Judy L Foxworth; Sara A Quandt; Phillip Summers; Francis O Walker; Thomas A Arcury Journal: J Agromedicine Date: 2015 Impact factor: 1.675
Authors: Michael C Schubert; Yoav Gimmon; Jennifer Millar; Kelly J Brewer; Dale Roberts; Mark Shelhamer; Charles Rohde; Jorge M Serrador Journal: PLoS One Date: 2018-12-26 Impact factor: 3.240