Literature DB >> 21406689

Inducible gene expression in mammals: plants add to the menu.

Sean R Cutler1.   

Abstract

Achieving inducible gene expression in mammalian cells with inexpensive and nontoxic inducers is an ongoing quest. The plant hormone abscisic acid has now been added to the list of compounds that can be used for regulating transcription and controlling protein function by induced proximity. These advances may enable new clinical applications of proximity-induced systems, and they highlight the value of fundamental research in plant biology.

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Year:  2011        PMID: 21406689     DOI: 10.1126/scisignal.2001875

Source DB:  PubMed          Journal:  Sci Signal        ISSN: 1945-0877            Impact factor:   8.192


  1 in total

1.  A novel TetR-regulating peptide turns off rtTA-mediated activation of gene expression.

Authors:  Sebastian Schmidt; Christian Berens; Marcus Klotzsche
Journal:  PLoS One       Date:  2014-05-08       Impact factor: 3.240

  1 in total

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