Literature DB >> 2140535

Association of a cytoplasmic dynein-like protein recognizable by anti-MAP 1C with the mammalian mitotic spindle.

T Yoshida1, K Katsuta, H Takanari, K Izutsu.   

Abstract

A rabbit antibody to bovine brain MAP 1C was prepared. The antibody stained the mitotic spindle of PtK2 cells by immunofluorescence. On immunoblots of PtK2 cell extract the antibody reacted with polypeptides of molecular weights greater than 350 and 80 KD that resemble the subunit proteins of bovine brain MAP 1C. An additional 135 KD polypeptide in the extract was also stained. These results indicate that a cytoplasmic dynein recognizable by the anti-MAP 1C antibody is localized in the mitotic spindle.

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Year:  1990        PMID: 2140535     DOI: 10.1016/s0309-1651(05)80001-3

Source DB:  PubMed          Journal:  Cell Biol Int Rep        ISSN: 0309-1651


  2 in total

1.  Low cytoplasmic pH causes fragmentation and dispersal of the Golgi apparatus in human hepatoma cells.

Authors:  T Yoshida; T Kamiya; K Imanaka-Yoshida; T Sakakura
Journal:  Int J Exp Pathol       Date:  1999-02       Impact factor: 1.925

2.  Brain dynein (MAP1C) localizes on both anterogradely and retrogradely transported membranous organelles in vivo.

Authors:  N Hirokawa; R Sato-Yoshitake; T Yoshida; T Kawashima
Journal:  J Cell Biol       Date:  1990-09       Impact factor: 10.539

  2 in total

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