Literature DB >> 21403848

An efficient micromixer based on multidirectional vortices due to baffles and channel curvature.

Rei-Tang Tsai1, Chih-Yang Wu.   

Abstract

An efficient planar micromixer based on multidirectional vortices in a curved channel with radial baffles is proposed and examined in this work. The curvature of the microchannel and the radial baffles induce vortices in different directions. The multidirectional vortices and the converging-diverging flow caused by the baffles contribute together to the enhancement of mixing. The micromixer is fabricated with polydimethylsiloxane by a single planar microlithography process and the mixing behaviors are observed by a confocal spectral microscope imaging system to validate the simulation obtained by a commercial code. The simulation and experimental results are in reasonable agreement. The concentration distributions and flow patterns obtained reveal the following trends. (i) The mixing efficiency of the basic C-shaped micromixer with the first baffle attached to the internal cylinder and the second attached to the external cylinder is better than that of the C-shaped micromixer with inverted arrangement of baffles. (ii) When the radius of the curved channel and the width of the passage between the baffle and the cylindrical wall are small enough and the Reynolds number (Re) is large enough, an extra separation vortex develops in the downstream of the second baffle. This phenomenon is one of the reasons of trend (i). (iii) A micromixer consisting of a few basic C-shaped micromixers connected by straight channels may generate a high degree of mixing for the case with a large Re.

Entities:  

Year:  2011        PMID: 21403848      PMCID: PMC3055903          DOI: 10.1063/1.3552992

Source DB:  PubMed          Journal:  Biomicrofluidics        ISSN: 1932-1058            Impact factor:   2.800


  5 in total

1.  Chaotic mixer for microchannels.

Authors:  Abraham D Stroock; Stephan K W Dertinger; Armand Ajdari; Igor Mezic; Howard A Stone; George M Whitesides
Journal:  Science       Date:  2002-01-25       Impact factor: 47.728

2.  Mixing processes in a zigzag microchannel: finite element simulations and optical study.

Authors:  Virginie Mengeaud; Jacques Josserand; Hubert H Girault
Journal:  Anal Chem       Date:  2002-08-15       Impact factor: 6.986

3.  Rapid diffusion of fluorescent tracers into Staphylococcus epidermidis biofilms visualized by time lapse microscopy.

Authors:  Suriani Abdul Rani; Betsey Pitts; Philip S Stewart
Journal:  Antimicrob Agents Chemother       Date:  2005-02       Impact factor: 5.191

4.  Design and integration of an all-in-one biomicrofluidic chip.

Authors:  Liyu Liu; Wenbin Cao; Jingbo Wu; Weijia Wen; Donald Choy Chang; Ping Sheng
Journal:  Biomicrofluidics       Date:  2008-07-21       Impact factor: 2.800

5.  Design and optimization of a double-enzyme glucose assay in microfluidic lab-on-a-chip.

Authors:  Yegermal Tesfaw Atalay; Daan Witters; Steven Vermeir; Nicolas Vergauwe; Pieter Verboven; Bart Nicolaï; Jeroen Lammertyn
Journal:  Biomicrofluidics       Date:  2009-10-19       Impact factor: 2.800

  5 in total
  14 in total

1.  Optimization of an electrokinetic mixer for microfluidic applications.

Authors:  Hendryk Bockelmann; Vincent Heuveline; Dominik P J Barz
Journal:  Biomicrofluidics       Date:  2012-05-24       Impact factor: 2.800

2.  An effective splitting-and-recombination micromixer with self-rotated contact surface for wide Reynolds number range applications.

Authors:  Xiangsong Feng; Yukun Ren; Hongyuan Jiang
Journal:  Biomicrofluidics       Date:  2013-10-28       Impact factor: 2.800

3.  Effect of the crossing-structure sequence on mixing performance within three-dimensional micromixers.

Authors:  Xiangsong Feng; Yukun Ren; Hongyuan Jiang
Journal:  Biomicrofluidics       Date:  2014-06-02       Impact factor: 2.800

4.  High-throughput inertial particle focusing in a curved microchannel: Insights into the flow-rate regulation mechanism and process model.

Authors:  Nan Xiang; Hong Yi; Ke Chen; Dongke Sun; Di Jiang; Qing Dai; Zhonghua Ni
Journal:  Biomicrofluidics       Date:  2013-08-08       Impact factor: 2.800

5.  A Planar Microfluidic Mixer Based on Logarithmic Spirals.

Authors:  Thomas Scherr; Christian Quitadamo; Preston Tesvich; Daniel Sang-Won Park; Terrence Tiersch; Daniel Hayes; Jin-Woo Choi; Krishnaswamy Nandakumar; W Todd Monroe
Journal:  J Micromech Microeng       Date:  2012       Impact factor: 1.881

6.  Increased density and coverage uniformity of viruses on a sensor surface by using U-type, T-type, and W-type microfluidic devices.

Authors:  Chia-Che Wu; Ping-Kuo Tseng; Ching-Hsiu Tsai; Yao-Lung Liu
Journal:  Biomicrofluidics       Date:  2012-05-24       Impact factor: 2.800

7.  Microfluidic mixing: a review.

Authors:  Chia-Yen Lee; Chin-Lung Chang; Yao-Nan Wang; Lung-Ming Fu
Journal:  Int J Mol Sci       Date:  2011-05-18       Impact factor: 5.923

8.  Integrated Immunomagnetic Bead-Based Microfluidic Chip for Exosomes Isolation.

Authors:  Fuzhou Niu; Xifu Chen; Xuemei Niu; Yifan Cai; Qingkui Zhang; Tao Chen; Hao Yang
Journal:  Micromachines (Basel)       Date:  2020-05-15       Impact factor: 2.891

Review 9.  A Review on Micromixers.

Authors:  Gaozhe Cai; Li Xue; Huilin Zhang; Jianhan Lin
Journal:  Micromachines (Basel)       Date:  2017-09-11       Impact factor: 2.891

10.  A "twisted" microfluidic mixer suitable for a wide range of flow rate applications.

Authors:  Shilpa Sivashankar; Sumeyra Agambayev; Yousof Mashraei; Er Qiang Li; Sigurdur T Thoroddsen; Khaled Nabil Salama
Journal:  Biomicrofluidics       Date:  2016-06-27       Impact factor: 2.800

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.