Literature DB >> 21403452

[5-FU/l-LV therapy is useful for hemodialysis patients with advanced gastric cancer].

Yusuke Saito1, Ken Shimada, Yasufumi Ohno, Hirokazu Toshima, Koji Kobayashi, Koichiro Miyashita, Shizuma Tsuchiya, Yasutaka Takinishi, Akio Miyokawa, Tomohiro Itoh, Akiko Sakashita.   

Abstract

A 71-year-old man receiving maintenance dialysis because of diabetic nephropathy presented with hematemesis at another hospital in January 2008. A gastrointestinal endoscopy demonstrated a II a-like lesion in the angle of the stomach, and he was admitted to our hospital. A diagnosis of gastric adenocarcinoma (cT2N2M0, Stage IIIA) was made. An operation could not be performed because of the high risk, so combination chemotherapy with 5-FU and l-LV was initiated. After 3 courses of treatment, the size of the primary tumor was markedly reduced. After 6 courses, the primary lesion had changed to a scar, and an endoscopic biopsy revealed no cancer cells. His performance status did not deteriorate, and no serious adverse events occurred during the course of treatment. Chemotherapy was continued because the overall response was SD. 5-FU/l-LV therapy should be considered as a safe and useful treatment for a hemodialysis patient with advanced gastric cancer.

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Year:  2011        PMID: 21403452

Source DB:  PubMed          Journal:  Gan To Kagaku Ryoho        ISSN: 0385-0684


  2 in total

1.  Safety of Regular-Dose Imatinib Therapy in Patients with Gastrointestinal Stromal Tumors Undergoing Dialysis.

Authors:  Ryota Niikura; Takako Serizawa; Atsuo Yamada; Shuntaro Yoshida; Mariko Tanaka; Yoshihiro Hirata; Kazuhiko Koike
Journal:  Case Rep Gastroenterol       Date:  2016-05-19

2.  Management of patients with end-stage renal disease undergoing chemotherapy: recommendations of the Associazione Italiana di Oncologia Medica (AIOM) and the Società Italiana di Nefrologia (SIN).

Authors:  Paolo Pedrazzoli; Nicola Silvestris; Antonio Santoro; Simona Secondino; Oronzo Brunetti; Vito Longo; Elena Mancini; Sara Mariucci; Teresa Rampino; Sara Delfanti; Silvia Brugnatelli; Saverio Cinieri
Journal:  ESMO Open       Date:  2017-07-19
  2 in total

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