Literature DB >> 21401884

Clinical experiences derived from implementation of an easy to use concept for treatment of wound healing by secondary intention and guidance in selection of appropriate dressings.

Chris Braumann1, Nina Guenther, Charalambos Menenakos, Helga Muenzberg, Matthias Pirlich, Herbert Lochs, Joachim M Mueller.   

Abstract

The main objective of this case-cohort-type observational study conducted at different Surgical Departments of the Charité-Universitätsmedizin in Berlin was to evaluate the sequential use concept first described by Systagenix Wound Management in 2007. Fifty-two patients with different wound healing by secondary intention were treated for 7 weeks at the Charité-Universitätsmedizin in Berlin. A multidisciplinary team worked together to reach consensus in wound assessment; in classification of infection status according to the criteria described by European Wound Management Association (EWMA); in treatment protocol and on dressings to be used to 'cover' wounds. Before dressing application, all wounds were cleaned from debris. Following the sequential use concept, wounds classified as stages 2 and 3 were dressed with SILVERCEL(®) and TIELLE(®) or TIELLE PLUS(®) to 'clean' the wounds. After 2-3 weeks, treatment was changed to PROMOGRAN PRISMA(®) and TIELLE(®) to 'close and cover' wounds, thus providing optimal wound healing. Wounds classified as non infected were dressed with PROMOGRAN PRISMA(®) and TIELLE(®) during the complete treatment period. Patients were asked to evaluate the treatment using a simplified questionnaire developed at the Charité-Universitätsmedizin in Berlin. Wounds comprised 37 surgical procedures, 8 chronic mixed ulcer, 4 pressure sores, 1 diabetic foot ulcer, 1 venous leg ulcer, and 1 mixed arterial/venous ulcer. At baseline, 12 wounds were classified as stage 3, 38 wounds as stage 2 and 2 wounds as stage 1. After 7 weeks of treatment, all patients showed a positive clinical response to the sequential use treatment. Results of wound size showed a high significant progression of wound healing expressed with a profound reduction of wound area (P in all measurements <0·001, chi-square test) and improved granulation. This study summarises the clinical experiences derived from the evaluation of the sequential use concept in the daily clinical practice of wound treatment. On the basis of the wound healing results, patients' evaluation of treatment and the clinicians' and staff experiences, this concept was implemented at different Surgical Departments of the Charité-Universitätsmedizin in Berlin.
© 2011 The Authors. © 2011 Blackwell Publishing Ltd and Medicalhelplines.com Inc.

Entities:  

Mesh:

Substances:

Year:  2011        PMID: 21401884      PMCID: PMC7950689          DOI: 10.1111/j.1742-481X.2011.00777.x

Source DB:  PubMed          Journal:  Int Wound J        ISSN: 1742-4801            Impact factor:   3.315


  9 in total

1.  Contact-free spectroscopy of leg ulcers: principle, technique, and calculation of spectroscopic wound scores.

Authors:  W D Schmidt; K Liebold; D Fassler; U Wollina
Journal:  J Invest Dermatol       Date:  2001-04       Impact factor: 8.551

Review 2.  Wound bed preparation: a systematic approach to wound management.

Authors:  Gregory S Schultz; R Gary Sibbald; Vincent Falanga; Elizabeth A Ayello; Caroline Dowsett; Keith Harding; Marco Romanelli; Michael C Stacey; Luc Teot; Wolfgang Vanscheidt
Journal:  Wound Repair Regen       Date:  2003-03       Impact factor: 3.617

3.  Interactions of cytokines, growth factors, and proteases in acute and chronic wounds.

Authors:  B A Mast; G S Schultz
Journal:  Wound Repair Regen       Date:  1996-10       Impact factor: 3.617

4.  Evaluation of Tielle hydropolymer dressings in the management of chronic exuding wounds in primary care.

Authors:  Curt Diehm; Holger Lawall
Journal:  Int Wound J       Date:  2005-03       Impact factor: 3.315

Review 5.  Topical silver for treating infected wounds.

Authors:  H Vermeulen; J M van Hattem; M N Storm-Versloot; D T Ubbink
Journal:  Cochrane Database Syst Rev       Date:  2007-01-24

Review 6.  What materials for dressings?

Authors:  J C Lawrence
Journal:  Injury       Date:  1982-05       Impact factor: 2.586

7.  Mechanism of action of PROMOGRAN, a protease modulating matrix, for the treatment of diabetic foot ulcers.

Authors:  Breda Cullen; Rachel Smith; Elaine McCulloch; Derek Silcock; Libby Morrison
Journal:  Wound Repair Regen       Date:  2002 Jan-Feb       Impact factor: 3.617

8.  Some effects of a topical collagen-based matrix on the microcirculation and wound healing in patients with chronic venous leg ulcers: preliminary observations.

Authors:  Uwe Wollina; Wolf-Dieter Schmidt; Claudia Krönert; Cornelia Nelskamp; Armin Scheibe; Dieter Fassler
Journal:  Int J Low Extrem Wounds       Date:  2005-12       Impact factor: 2.057

9.  Evaluation of a silver-releasing hydroalginate dressing in chronic wounds with signs of local infection.

Authors:  S Meaume; D Vallet; M Nguyen Morere; L Téot
Journal:  J Wound Care       Date:  2005-10       Impact factor: 2.072

  9 in total
  5 in total

Review 1.  Topical antimicrobial agents for treating foot ulcers in people with diabetes.

Authors:  Jo C Dumville; Benjamin A Lipsky; Christopher Hoey; Mario Cruciani; Marta Fiscon; Jun Xia
Journal:  Cochrane Database Syst Rev       Date:  2017-06-14

2.  Treatment options for postoperatively infected abdominal wall wounds healing by secondary intention.

Authors:  Julia Mees; Wolf Arif Mardin; Norbert Senninger; Matthias Bruewer; Daniel Palmes; Soeren Torge Mees
Journal:  Langenbecks Arch Surg       Date:  2012-08-10       Impact factor: 3.445

Review 3.  The diagnosis of infection in chronic leg ulcers: A narrative review on clinical practice.

Authors:  Ut T Bui; Kathleen Finlayson; Helen Edwards
Journal:  Int Wound J       Date:  2019-01-29       Impact factor: 3.315

Review 4.  Oxidized Regenerated Cellulose/Collagen Dressings: Review of Evidence and Recommendations.

Authors:  Stephanie Wu; Andrew J Applewhite; Jeffrey Niezgoda; Robert Snyder; Jayesh Shah; Breda Cullen; Gregory Schultz; Janis Harrison; Rosemary Hill; Melania Howell; Marcus Speyrer; Howard Utra; Jean de Leon; Wayne Lee; Terry Treadwell
Journal:  Adv Skin Wound Care       Date:  2017-11       Impact factor: 2.347

5.  Application of hyaluronic acid in the healing of non-experimental open wounds: A pilot study on 12 wounds in 10 client-owned dogs.

Authors:  Roberta Ferrari; Patrizia Boracchi; Stefano Romussi; Giuliano Ravasio; Damiano Stefanello
Journal:  Vet World       Date:  2015-10-28
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.