Literature DB >> 21401043

Measurement and estimation of electrophilic reactivity for predictive toxicology.

Johannes A H Schwöbel1, Yana K Koleva, Steven J Enoch, Fania Bajot, Mark Hewitt, Judith C Madden, David W Roberts, Terry W Schultz, Mark T D Cronin.   

Abstract

Mesh：

Year:  2011        PMID： 21401043     DOI： 10.1021/cr100098n

Source DB:  PubMed          Journal:  Chem Rev        ISSN： 0009-2665            Impact factor:   60.622


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  34 in total

1.  Monohalogenated acetamide-induced cellular stress and genotoxicity are related to electrophilic softness and thiol/thiolate reactivity.

Authors:  Justin A Pals; Elizabeth D Wagner; Michael J Plewa; Menghang Xia; Matias S Attene-Ramos
Journal:  J Environ Sci (China)       Date:  2017-05-09       Impact factor: 5.565

2.  Adverse outcome pathway development II: best practices.

Authors:  Daniel L Villeneuve; Doug Crump; Natàlia Garcia-Reyero; Markus Hecker; Thomas H Hutchinson; Carlie A LaLone; Brigitte Landesmann; Teresa Lettieri; Sharon Munn; Malgorzata Nepelska; Mary Ann Ottinger; Lucia Vergauwen; Maurice Whelan
Journal:  Toxicol Sci       Date:  2014-12       Impact factor: 4.849

3.  Selective Covalent Protein Modification by 4-Halopyridines through Catalysis.

Authors:  Christopher L Schardon; Alfred Tuley; Joyce A V Er; Jake C Swartzel; Walter Fast
Journal:  Chembiochem       Date:  2017-06-27       Impact factor: 3.164

4.  Mechanistic understanding of molecular initiating events (MIEs) using NMR spectroscopy.

Authors:  Paul N Sanderson; Wendy Simpson; Richard Cubberley; Maja Aleksic; Stephen Gutsell; Paul J Russell
Journal:  Toxicol Res (Camb)       Date:  2015-09-15       Impact factor: 3.524

5.  Synthesis, anticancer activity, and molecular modeling of 1,4-naphthoquinones that inhibit MKK7 and Cdc25.

Authors:  Igor A Schepetkin; Alexander S Karpenko; Andrei I Khlebnikov; Marina O Shibinska; Igor A Levandovskiy; Liliya N Kirpotina; Nadezhda V Danilenko; Mark T Quinn
Journal:  Eur J Med Chem       Date:  2019-09-18       Impact factor: 6.514

Review 6.  Application of the Hard and Soft, Acids and Bases (HSAB) theory to toxicant--target interactions.

Authors:  Richard M Lopachin; Terrence Gavin; Anthony Decaprio; David S Barber
Journal:  Chem Res Toxicol       Date:  2011-11-16       Impact factor: 3.739

Review 7.  Selective and Effective: Current Progress in Computational Structure-Based Drug Discovery of Targeted Covalent Inhibitors.

Authors:  Giulia Bianco; David S Goodsell; Stefano Forli
Journal:  Trends Pharmacol Sci       Date:  2020-11-02       Impact factor: 14.819

8.  Pyridoxylamine reactivity kinetics as an amine based nucleophile for screening electrophilic dermal sensitizers.

Authors:  Itai Chipinda; Wilbes Mbiya; Risikat Ajibola Adigun; Moshood K Morakinyo; Brandon F Law; Reuben H Simoyi; Paul D Siegel
Journal:  Toxicology       Date:  2013-12-12       Impact factor: 4.221

Review 9.  Redox Signaling by Reactive Electrophiles and Oxidants.

Authors:  Saba Parvez; Marcus J C Long; Jesse R Poganik; Yimon Aye
Journal:  Chem Rev       Date:  2018-08-27       Impact factor: 60.622

Review 10.  Targeting Non-Catalytic Cysteine Residues Through Structure-Guided Drug Discovery.

Authors:  Kenneth K Hallenbeck; David M Turner; Adam R Renslo; Michelle R Arkin
Journal:  Curr Top Med Chem       Date:  2017       Impact factor: 3.295
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