Literature DB >> 21400749

[Experimental study of Ingavirin antiviral activity against human adenovirus].

V V Zarubaev, A V Slita, A K Sirotkin, V E Nebol'sin, O I Kiselev.   

Abstract

Antiviral properties of Ingavirin were investigated in the Hep-2 cell culture with respect to the human respiratory tract virus (type 5 adenovirus). In concentrations of Ingavirin of 1000, 100 and 10 mcg/ml the generated posterity showed lower infective capacity (by 250, 100 and 10 times respectively). The electron microscopy of the infected cells confirmed the Ingavirin ability to disturb the adenovirus normal morphogenesis.

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Year:  2010        PMID： 21400749

Source DB:  PubMed          Journal:  Antibiot Khimioter        ISSN： 0235-2990


  2 in total

1.  Activity of Ingavirin (6-[2-(1H-Imidazol-4-yl)ethylamino]-5-oxo-hexanoic Acid) Against Human Respiratory Viruses in in Vivo Experiments.

Authors:  Vladimir V Zarubaev; Angelica V Garshinina; Nelly A Kalinina; Anna A Shtro; Svetlana V Belyaevskaya; Alexander V Slita; Vladimir E Nebolsin; Oleg I Kiselev
Journal:  Pharmaceuticals (Basel)       Date:  2011-11-25

2.  Antiviral Activity of Exopolysaccharides Produced by Lactic Acid Bacteria of the Genera Pediococcus, Leuconostoc and Lactobacillus against Human Adenovirus Type 5.

Authors:  Liubov Biliavska; Yulia Pankivska; Olga Povnitsa; Svitlana Zagorodnya
Journal:  Medicina (Kaunas)       Date:  2019-08-22       Impact factor: 2.430
  2 in total

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