| Literature DB >> 21400199 |
Joyce Aparecida Martins1, Raquel de Freitas Figueiredo, Cyntia Sumie Yoshizaki, Greiciane Gaburro Paneto, Regina Maria Barretto Cicarelli.
Abstract
The genetic markers most commonly utilized to determine identity and in paternity testing are autosomal short tandem repeats (STRs); to interpret the DNA analysis, the results of a case have to be compared with a pertinent reference population. Thus, the aim of this work was to characterize the genetic profile of the population of Araraquara (São Paulo, Brazil) by analyzing 15 STR loci included in the PowerPlex(®) 16 System and to correlate these data with the migration history of the population. No deviations from the Hardy-Weinberg equilibrium were observed for any of the loci, after Bonferroni's correction. Forensic parameters exhibited high values, the most polymorphic loci being Penta E, D18S51 and FGA. An unweighted pair-group method with arithmetic mean (UPGMA) tree based on genetic distances showed that the current population of Araraquara is grouped with populations of the southeastern region of Brazil, which are close to the European group but distant from African and Amerindian populations. Estimates of admixture components revealed that the contributions to the population of Araraquara were 76% European, 18% African, and 6% Amerindian.Entities:
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Year: 2011 PMID: 21400199 DOI: 10.1007/s11033-011-0693-6
Source DB: PubMed Journal: Mol Biol Rep ISSN: 0301-4851 Impact factor: 2.316