| Literature DB >> 21399709 |
Mauricio Hoyos1, Lee Moore, P Stephen Williams, Maciej Zborowski.
Abstract
The Quadrupole Magnetic Sorter (QMS), employing an annular flow channel concentric with the aperture of a quadrupole magnet, is well established for cell and particle separations. Here we propose a magnetic particle separator comprising a linear array of cylindrical magnets, analogous to the array proposed by Klaus Halbach, mated to a substantially improved form of parallel-plate SPLITT channel, known as the step-SPLITT channel. While the magnetic force and throughput are generally lower than for the QMS, the new separator has advantages in ease of fabrication and the ability to vary the magnetic force to suit the separands. Preliminary experiments yield results consistent with prediction and show promise regarding future separations of cells of biomedical interest.Entities:
Year: 2011 PMID: 21399709 PMCID: PMC3050493 DOI: 10.1016/j.jmmm.2010.11.051
Source DB: PubMed Journal: J Magn Magn Mater ISSN: 0304-8853 Impact factor: 2.993