Literature DB >> 21399709

The use of a linear Halbach array combined with a step-SPLITT channel for continuous sorting of magnetic species.

Mauricio Hoyos1, Lee Moore, P Stephen Williams, Maciej Zborowski.   

Abstract

The Quadrupole Magnetic Sorter (QMS), employing an annular flow channel concentric with the aperture of a quadrupole magnet, is well established for cell and particle separations. Here we propose a magnetic particle separator comprising a linear array of cylindrical magnets, analogous to the array proposed by Klaus Halbach, mated to a substantially improved form of parallel-plate SPLITT channel, known as the step-SPLITT channel. While the magnetic force and throughput are generally lower than for the QMS, the new separator has advantages in ease of fabrication and the ability to vary the magnetic force to suit the separands. Preliminary experiments yield results consistent with prediction and show promise regarding future separations of cells of biomedical interest.

Entities:  

Year:  2011        PMID: 21399709      PMCID: PMC3050493          DOI: 10.1016/j.jmmm.2010.11.051

Source DB:  PubMed          Journal:  J Magn Magn Mater        ISSN: 0304-8853            Impact factor:   2.993


  5 in total

1.  Flow rate optimization for the quadrupole magnetic cell sorter.

Authors:  P S Williams; M Zborowski; J J Chalmers
Journal:  Anal Chem       Date:  1999-09-01       Impact factor: 6.986

2.  The use of magnetite-doped polymeric microspheres in calibrating cell tracking velocimetry.

Authors:  L R Moore; M Zborowski; M Nakamura; K McCloskey; S Gura; M Zuberi; S Margel; J J Chalmers
Journal:  J Biochem Biophys Methods       Date:  2000-07-10

3.  Particle sorting in a mini step-split-flow thin channel: influence of hydrodynamic shear on transversal migration.

Authors:  Natacha Callens; Mauricio Hoyos; Pascal Kurowski; Carlo S Iorio
Journal:  Anal Chem       Date:  2008-05-31       Impact factor: 6.986

4.  Separation of a breast cancer cell line from human blood using a quadrupole magnetic flow sorter.

Authors:  M Nakamura; K Decker; J Chosy; K Comella; K Melnik; L Moore; L C Lasky; M Zborowski; J J Chalmers
Journal:  Biotechnol Prog       Date:  2001 Nov-Dec

5.  Characterization of nonspecific crossover in split-flow thin channel fractionation.

Authors:  P Stephen Williams; Mauricio Hoyos; Pascal Kurowski; Dorra Salhi; Lee R Moore; Maciej Zborowski
Journal:  Anal Chem       Date:  2008-08-13       Impact factor: 6.986

  5 in total
  3 in total

1.  Resistive pulse sensing of magnetic beads and supraparticle structures using tunable pores.

Authors:  Geoff R Willmott; Mark Platt; Gil U Lee
Journal:  Biomicrofluidics       Date:  2012-01-12       Impact factor: 2.800

2.  On-chip magnetophoretic isolation of CD4 + T cells from blood.

Authors:  Jeff Darabi; Chuan Guo
Journal:  Biomicrofluidics       Date:  2013-09-11       Impact factor: 2.800

3.  Inverted Linear Halbach Array for Separation of Magnetic Nanoparticles.

Authors:  Y Ijiri; C Poudel; P S Williams; L R Moore; T Orita; M Zborowski
Journal:  IEEE Trans Magn       Date:  2013-07       Impact factor: 1.700

  3 in total

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